The Baroreflex in Hypertension

Overview

Journal Curr Hypertens Rep

Specialty Cardiology & Vascular Diseases

Date 2015 Mar 11

PMID 25754323

Citations 8

Authors

Genaro Fernandez

Junsoo Alex Lee

Lynn C Liu

John P Gassler

Affiliations

Soon will be listed here.

Abstract

Hypertension is a complex syndrome that increases the risk of developing other medical comorbidities and interacts with other medical conditions to increase the risk of target end-organ damage such as cardiovascular disease, stroke, and renal disease. Hypertension remains under-recognized and poorly controlled in the USA and worldwide. In some patients, hypertension is resistant to optimal medical therapy. Over the last few decades, there has been an increasing understanding of the role of the sympathetic nervous system in the development and maintenance of hypertension. This update reviews the physiology and role of the sympathetic nervous system in hypertension and pharmacological and interventional treatments directed at nervous system involvement in secondary hypertension.

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