Robotics in the Neurosurgical Treatment of Glioma

Overview

Journal Surg Neurol Int

Specialty Neurology

Date 2015 Feb 28

PMID 25722932

Citations 16

Authors

Garnette R Sutherland

Yaser Maddahi

Liu Shi Gan

Sanju Lama

Kourosh Zareinia

Affiliations

Soon will be listed here.

Abstract

Background: The treatment of glioma remains a significant challenge with high recurrence rates, morbidity, and mortality. Merging image guided robotic technology with microsurgery adds a new dimension as they relate to surgical ergonomics, patient safety, precision, and accuracy.

Methods: An image-guided robot, called neuroArm, has been integrated into the neurosurgical operating room, and used to augment the surgical treatment of glioma in 18 patients. A case study illustrates the specialized technical features of a teleoperated robotic system that could well enhance the performance of surgery. Furthermore, unique positional and force information of the bipolar forceps during surgery were recorded and analyzed.

Results: The workspace of the bipolar forceps in this robot-assisted glioma resection was found to be 25 × 50 × 50 mm. Maximum values of the force components were 1.37, 1.84, and 2.01 N along x, y, and z axes, respectively. The maximum total force was 2.45 N. The results indicate that the majority of the applied forces were less than 0.6 N.

Conclusion: Robotic surgical systems can potentially increase safety and performance of surgical operation via novel features such as virtual fixtures, augmented force feedback, and haptic high-force warning system. The case study using neuroArm robot to resect a glioma, for the first time, showed the positional information of surgeon's hand movement and tool-tissue interaction forces.

Citing Articles

Bridging the Global Technology Gap in Neurosurgery: Disparities in Access to Advanced Tools for Brain Tumor Resection.

Valerio J, Ramirez-Velandia F, Fernandez-Gomez M, Rea N, Alvarez-Pinzon A Neurosurg Pract. 2025; 5(2):e00090.

PMID: 39958239 PMC: 11783611. DOI: 10.1227/neuprac.0000000000000090.

7 T and beyond: toward a synergy between fMRI-based presurgical mapping at ultrahigh magnetic fields, AI, and robotic neurosurgery.

L Seghier M Eur Radiol Exp. 2024; 8(1):73.

PMID: 38945979 PMC: 11214939. DOI: 10.1186/s41747-024-00472-y.

The role of robotic surgery in neurological cases: A systematic review on brain and spine applications.

Lin T, Xie Q, Peng T, Zhao X, Chen D Heliyon. 2023; 9(12):e22523.

PMID: 38046149 PMC: 10686875. DOI: 10.1016/j.heliyon.2023.e22523.

Microsurgery Robots: Applications, Design, and Development.

Wang T, Li H, Pu T, Yang L Sensors (Basel). 2023; 23(20).

PMID: 37896597 PMC: 10611418. DOI: 10.3390/s23208503.

Advances in artificial intelligence, robotics, augmented and virtual reality in neurosurgery.

Kazemzadeh K, Akhlaghdoust M, Zali A Front Surg. 2023; 10:1241923.

PMID: 37693641 PMC: 10483402. DOI: 10.3389/fsurg.2023.1241923.

References

Silbergeld D, Chicoine M . Isolation and characterization of human malignant glioma cells from histologically normal brain. J Neurosurg. 1997; 86(3):525-31. DOI: 10.3171/jns.1997.86.3.0525. View

Wedeen V, Rosene D, Wang R, Dai G, Mortazavi F, Hagmann P . The geometric structure of the brain fiber pathways. Science. 2012; 335(6076):1628-34. PMC: 3773464. DOI: 10.1126/science.1215280. View

Assaf Y, Pasternak O . Diffusion tensor imaging (DTI)-based white matter mapping in brain research: a review. J Mol Neurosci. 2007; 34(1):51-61. DOI: 10.1007/s12031-007-0029-0. View

Matthews P, Honey G, Bullmore E . Applications of fMRI in translational medicine and clinical practice. Nat Rev Neurosci. 2006; 7(9):732-44. DOI: 10.1038/nrn1929. View

Sutherland G, Wolfsberger S, Lama S, Zarei-nia K . The evolution of neuroArm. Neurosurgery. 2012; 72 Suppl 1:27-32. DOI: 10.1227/NEU.0b013e318270da19. View

Prasad S, Prasad S, Maniar H, Chu C, Schuessler R, Damiano Jr R . Surgical robotics: impact of motion scaling on task performance. J Am Coll Surg. 2004; 199(6):863-8. DOI: 10.1016/j.jamcollsurg.2004.08.027. View

Camarillo D, Krummel T, Salisbury Jr J . Robotic technology in surgery: past, present, and future. Am J Surg. 2004; 188(4A Suppl):2S-15S. DOI: 10.1016/j.amjsurg.2004.08.025. View

Sutherland G, Lama S, Gan L, Wolfsberger S, Zareinia K . Merging machines with microsurgery: clinical experience with neuroArm. J Neurosurg. 2012; 118(3):521-9. DOI: 10.3171/2012.11.JNS12877. View

Nimsky C, Ganslandt O, Hastreiter P, Wang R, Benner T, Sorensen A . Preoperative and intraoperative diffusion tensor imaging-based fiber tracking in glioma surgery. Neurosurgery. 2004; 56(1):130-7. DOI: 10.1227/01.neu.0000144842.18771.30. View

10.

McCormack B, Miller D, BUDZILOVICH G, Voorhees G, Ransohoff J . Treatment and survival of low-grade astrocytoma in adults--1977-1988. Neurosurgery. 1992; 31(4):636-42; discussion 642. DOI: 10.1227/00006123-199210000-00004. View

11.

Raethjen J, Pawlas F, Lindemann M, Wenzelburger R, Deuschl G . Determinants of physiologic tremor in a large normal population. Clin Neurophysiol. 2000; 111(10):1825-37. DOI: 10.1016/s1388-2457(00)00384-9. View

12.

Hill D, Maurer Jr C, Maciunas R, Barwise J, Fitzpatrick J, Wang M . Measurement of intraoperative brain surface deformation under a craniotomy. Neurosurgery. 1998; 43(3):514-26; discussion 527-8. DOI: 10.1097/00006123-199809000-00066. View

13.

Rath B, Fair J, Jamal M, Camphausen K, Tofilon P . Astrocytes enhance the invasion potential of glioblastoma stem-like cells. PLoS One. 2013; 8(1):e54752. PMC: 3551925. DOI: 10.1371/journal.pone.0054752. View

14.

Ottensmeyer M, Salisbury J . Input and output for surgical simulation: devices to measure tissue properties in vivo and a haptic interface for laparoscopy simulators. Stud Health Technol Inform. 2000; 70:236-42. View

15.

Sutherland G, Latour I, Greer A . Integrating an image-guided robot with intraoperative MRI: a review of the design and construction of neuroArm. IEEE Eng Med Biol Mag. 2008; 27(3):59-65. DOI: 10.1109/EMB.2007.910272. View

16.

Kuhnt D, Bauer M, Nimsky C . Brain shift compensation and neurosurgical image fusion using intraoperative MRI: current status and future challenges. Crit Rev Biomed Eng. 2012; 40(3):175-85. DOI: 10.1615/critrevbiomedeng.v40.i3.20. View

17.

Dorward N, Alberti O, Velani B, Gerritsen F, Harkness W, Kitchen N . Postimaging brain distortion: magnitude, correlates, and impact on neuronavigation. J Neurosurg. 1998; 88(4):656-62. DOI: 10.3171/jns.1998.88.4.0656. View

18.

Watts C, Price S, Santarius T . Current concepts in the surgical management of glioma patients. Clin Oncol (R Coll Radiol). 2014; 26(7):385-94. DOI: 10.1016/j.clon.2014.04.001. View

19.

Black P, Moriarty T, Alexander 3rd E, Stieg P, Woodard E, Gleason P . Development and implementation of intraoperative magnetic resonance imaging and its neurosurgical applications. Neurosurgery. 1997; 41(4):831-42; discussion 842-5. DOI: 10.1097/00006123-199710000-00013. View

20.

Koch C, Laurent G . Complexity and the nervous system. Science. 1999; 284(5411):96-8. DOI: 10.1126/science.284.5411.96. View