Short-term Changes in Light Distortion in Orthokeratology Subjects

Overview

Journal Biomed Res Int

Publisher Wiley

Specialties Biomedical Engineering
Biotechnology
General Medicine

Date 2015 Feb 21

PMID 25699265

Citations 12

Authors

Elena Santolaria Sanz

Alejandro Cervino

Antonio Queiros

Cesar Villa-Collar

Daniela Lopes-Ferreira

Jose Manuel Gonzalez-Meijome

Affiliations

Soon will be listed here.

Abstract

Purpose: Quantifying adaptation to light distortion of subjects undergoing orthokeratology (OK) for myopia during the first month of treatment.

Methods: Twenty-nine healthy volunteers (age: 22.34 ± 8.08 years) with mean spherical equivalent refractive error -2.10 ± 0.93D were evaluated at baseline and days 1, 7, 15, and 30 of OK treatment. Light distortion was determined using an experimental prototype. Corneal aberrations were derived from corneal topography for different pupil sizes. Contrast sensitivity function (CSF) was analyzed for frequencies of 1.50, 2.12, 3.00, 4.24, 6.00, 8.49, 12.00, 16.97, and 24.00 cpd under photopic conditions.

Results: Average monocular values of all light distortion parameters measured increased significantly on day 1, returning to baseline after 1 week (P < 0.05 in all cases). Spherical-like aberration stabilized on day 7 for all pupil diameters, while coma-like for smaller pupils only. CSF was significantly reduced on day 1 for all spatial frequencies except for 1.5 cpd, returning to baseline afterwards. Significant correlation was found between light distortion and contrast sensitivity for middle and high frequencies (P < 0.05) after 15 days.

Conclusion: Despite consistently increased levels of corneal aberrations, light distortion tends to return to baseline after one week of treatment, suggesting that neural adaptation is capable of overcoming optical quality degradation.

Citing Articles

Peripheral Defocus in Orthokeratology Myopia Correction: Systematic Review and Meta-Analysis.

Queiros A, Pinheiro I, Fernandes P J Clin Med. 2025; 14(3).

PMID: 39941333 PMC: 11818867. DOI: 10.3390/jcm14030662.

The effect of orthokeratology lenses on optical quality and visual function in children.

Lu W, Song G, Zhang Y, Lian Y, Ma K, Lu Q Front Neurosci. 2023; 17:1142524.

PMID: 37123367 PMC: 10140410. DOI: 10.3389/fnins.2023.1142524.

Time Course of Perceived Visual Distortion and Axial Length Growth in Myopic Children Undergoing Orthokeratology.

Liu G, Wu Y, Bi H, Wang B, Gu T, Du B Front Neurosci. 2021; 15:693217.

PMID: 34720848 PMC: 8548729. DOI: 10.3389/fnins.2021.693217.

Blur Detection Sensitivity Increases in Children Using Orthokeratology.

Xu J, Tao C, Mao X, Lu X, Bao J, Drobe B Front Neurosci. 2021; 15:630844.

PMID: 33790734 PMC: 8006440. DOI: 10.3389/fnins.2021.630844.

The Combined Effect of Low-dose Atropine with Orthokeratology in Pediatric Myopia Control: Review of the Current Treatment Status for Myopia.

Sanchez-Gonzalez J, De-Hita-Cantalejo C, Baustita-Llamas M, Sanchez-Gonzalez M, Capote-Puente R J Clin Med. 2020; 9(8).

PMID: 32722266 PMC: 7465046. DOI: 10.3390/jcm9082371.

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