Positive Immunolabelling for Feline Infectious Peritonitis in an African Lion (Panthera Leo) with Bilateral Panuveitis

Overview

Journal J Comp Pathol

Publisher Elsevier

Specialties Pathology
Veterinary Medicine

Date 2015 Feb 14

PMID 25678422

Citations 4

Authors

M Mwase

K Shimada

C Mumba

J Yabe

D Squarre

H Madarame

Affiliations

Soon will be listed here.

Abstract

A 15-year-old male African lion (Panthera leo) was presented with blindness due to bilateral panuveitis with retinal detachment. Feline coronavirus (FCoV) antigen was identified immunohistochemically in ocular macrophages, consistent with a diagnosis of feline infectious peritonitis (FIP) infection. This is the first report of FIP in an African lion and the first report of ocular FIP in a non-domestic felid.

Citing Articles

Evolutionary Dynamics and Epidemiology of Endemic and Emerging Coronaviruses in Humans, Domestic Animals, and Wildlife.

Islam A, Ferdous J, Islam S, Sayeed M, Choudhury S, Saha O Viruses. 2021; 13(10).

PMID: 34696338 PMC: 8537103. DOI: 10.3390/v13101908.

SARS-CoV-2 and the Eye: Implications for the Retina Specialist from Human Coronavirus Outbreaks and Animal Models.

FRCOphth A, Shantha J, Li J, Faia L, Hartley C, Kuthyar S J Vitreoretin Dis. 2021; 4(5):411-419.

PMID: 33665540 PMC: 7928265. DOI: 10.1177/2474126420939723.

Pathology of Coronavirus Infections: A Review of Lesions in Animals in the One-Health Perspective.

Zappulli V, Ferro S, Bonsembiante F, Brocca G, Calore A, Cavicchioli L Animals (Basel). 2020; 10(12).

PMID: 33322366 PMC: 7764021. DOI: 10.3390/ani10122377.

Diagnosis of Feline Infectious Peritonitis: A Review of the Current Literature.

Felten S, Hartmann K Viruses. 2019; 11(11).

PMID: 31731711 PMC: 6893704. DOI: 10.3390/v11111068.

References

Bauer B, Kerr M, Sandmeyer L, Grahn B . Positive immunostaining for feline infectious peritonitis (FIP) in a Sphinx cat with cutaneous lesions and bilateral panuveitis. Vet Ophthalmol. 2013; 16 Suppl 1:160-3. PMC: 7169334. DOI: 10.1111/vop.12044. View

Kennedy M, Kania S, Stylianides E, Bertschinger H, Keet D, Van Vuuren M . Detection of feline coronavirus infection in southern African nondomestic felids. J Wildl Dis. 2003; 39(3):529-35. DOI: 10.7589/0090-3558-39.3.529. View

COLBY E, Low R . Feline infectious peritonitis. Vet Med Small Anim Clin. 1970; 65(8):783-6. View

Robison R, HOLZWORTH J, GILMORE C . Naturally occurring feline infectious peritonitis: signs and clinical diagnosis. J Am Vet Med Assoc. 1971; 158(6):Suppl 2:981-6. View

Stephenson N, Swift P, Moeller R, Worth S, Foley J . Feline infectious peritonitis in a mountain lion (Puma concolor), California, USA. J Wildl Dis. 2013; 49(2):408-12. DOI: 10.7589/2012-08-210. View

Bailey E, Smith C, Sudlow C, Wardlaw J . Pathology of lacunar ischemic stroke in humans--a systematic review. Brain Pathol. 2012; 22(5):583-91. PMC: 8057646. DOI: 10.1111/j.1750-3639.2012.00575.x. View

Foley J, Leutenegger C . A review of coronavirus infection in the central nervous system of cats and mice. J Vet Intern Med. 2001; 15(5):438-44. PMC: 7166525. DOI: 10.1892/0891-6640(2001)015<0438:arocii>2.3.co;2. View

Drechsler Y, Alcaraz A, Bossong F, Collisson E, Diniz P . Feline coronavirus in multicat environments. Vet Clin North Am Small Anim Pract. 2011; 41(6):1133-69. PMC: 7111326. DOI: 10.1016/j.cvsm.2011.08.004. View

Giori L, Giordano A, Giudice C, Grieco V, Paltrinieri S . Performances of different diagnostic tests for feline infectious peritonitis in challenging clinical cases. J Small Anim Pract. 2011; 52(3):152-7. PMC: 7166807. DOI: 10.1111/j.1748-5827.2011.01042.x. View

10.

Kipar A, Meli M . Feline infectious peritonitis: still an enigma?. Vet Pathol. 2014; 51(2):505-26. DOI: 10.1177/0300985814522077. View

11.

Hohdatsu T, Sasamoto T, Okada S, Koyama H . Antigenic analysis of feline coronaviruses with monoclonal antibodies (MAbs): preparation of MAbs which discriminate between FIPV strain 79-1146 and FECV strain 79-1683. Vet Microbiol. 1991; 28(1):13-24. PMC: 7117509. DOI: 10.1016/0378-1135(91)90096-x. View

12.

Doherty M . Ocular manifestations of feline infectious peritonitis. J Am Vet Med Assoc. 1971; 159(4):417-24. View