Positive Immunostaining for Feline Infectious Peritonitis (FIP) in a Sphinx Cat with Cutaneous Lesions and Bilateral Panuveitis

Overview

Journal Vet Ophthalmol

Specialties Ophthalmology
Veterinary Medicine

Date 2013 Apr 24

PMID 23607772

Citations 14

Authors

Bianca S Bauer

Moira E Kerr

Lynne S Sandmeyer

Bruce H Grahn

Affiliations

Soon will be listed here.

Abstract

Feline infectious peritonitis (FIP) is a common, fatal, systemic disease of cats. This case report describes the antemortem diagnosis of FIP in a 2-year-old spayed female Sphinx cat that presented with a bilateral panuveitis and multiple papular cutaneous lesions. Histopathologically, the skin lesions were characterized by perivascular infiltrates of macrophages, neutrophils, with fewer plasma cells, mast cells, and small lymphocytes in the mid- to deep dermis. Immunohistochemistry for intracellular feline coronavirus (FeCoV) antigen demonstrated positive staining in dermal macrophages providing an antemortem diagnosis of a moderate, nodular to diffuse, pyogranulomatous perivascular dermatitis due to FIP infection. Obtaining an antemortem diagnosis of FIP can be a challenge and cutaneous lesions are rare in the disease. Recognition and biopsy of any cutaneous lesions in cats with panuveitis and suspected FIP can help establish an antemortem diagnosis of the disease.

Citing Articles

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