Sex-based Differences in Skeletal Muscle Kinetics and Fiber-type Composition

Overview

Journal Physiology (Bethesda)

Specialty Physiology

Date 2015 Jan 7

PMID 25559153

Citations 192

Authors

K M Haizlip

B C Harrison

L A Leinwand

Affiliations

Soon will be listed here.

Abstract

Previous studies have identified over 3,000 genes that are differentially expressed in male and female skeletal muscle. Here, we review the sex-based differences in skeletal muscle fiber composition, myosin heavy chain expression, contractile function, and the regulation of these physiological differences by thyroid hormone, estrogen, and testosterone. The findings presented lay the basis for the continued work needed to fully understand the skeletal muscle differences between males and females.

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