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The Unexpected Evolution of Basic Science Studies About Cyclic Nucleotide Action into a Treatment for Erectile Dysfunction

Overview
Journal J Biol Chem
Specialty Biochemistry
Date 2014 Dec 16
PMID 25505249
Authors
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Abstract

In these Reflections, I describe my perceived role in discoveries made in the cyclic nucleotide field that culminated in the advent of PDE5 inhibitors that treat erectile dysfunction, such as Viagra, Levitra, and Cialis. The discoveries emphasize the critical role of basic science, which often evolves in unpredictable and circuitous paths, in improving human health.

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