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Gram-positive Antimicrobial Activity of Amino Acid-based Hydrogels

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Journal Adv Mater
Date 2014 Dec 3
PMID 25447243
Citations 29
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Abstract

Antimicrobial hydrogels are prepared based on the co-assembly of commercial Fmoc-phenylalanine and Fmoc-leucine, which act as the hydrogelator and antimicrobial building block, respectively. This co-assembled antimicrobial hydrogel is demonstrated to exhibit selective bactericidal activity for gram-positive bacteria while being biocompatible with normal mammalian cells, showing great potential as an antimicrobial coating for clinical anti-infective applications.

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