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Predominant CD4 T-lymphocyte Tropism of Human Herpesvirus 6-related Virus

Overview
Journal J Virol
Publisher American Society for Microbiology
Date 1989 Jul 1
PMID 2542623
Citations 91
Authors
K Takahashi
S Sonoda
K Higashi
T Kondo
H Takahashi
M Takahashi
K Yamanishi
Affiliations
Soon will be listed here.
Abstract

Human herpesvirus 6 (HHV-6)-related virus was isolated from CD4+ CD8- and CD3+ CD4+ mature T lymphocytes but could not be isolated from CD4- CD8+, CD4- CD8-, and CD3- T cells in the peripheral blood of exanthem subitum patients. HHV-6-related virus predominantly infected CD4+ CD8+, CD4+ CD8-, and CD3+ CD4+ cells with mature phenotypes and rarely infected CD4- CD8+ cells from cord blood mononuclear cells, which suggested predominant CD4 mature T-lymphocyte tropism of HHV-6-related virus.

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