Investigation of Varicella-zoster Virus Infection of Lymphocytes by in Situ Hybridization

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 1989 May 1

PMID 2539528

Citations 28

Authors

C M Koropchak

S M Solem

P S Diaz

A M Arvin

Affiliations

Soon will be listed here.

Abstract

Peripheral blood mononuclear cells harboring viral gene sequences were detected during primary varicella-zoster virus (VZV) infection of the human host and the strain 2 guinea pig by in situ hybridization with a 3H-labeled VZV DNA probe. Activated T lymphocytes were permissive for VZV infection at low frequency in vitro.

Citing Articles

Creating the "Dew Drop on a Rose Petal": the Molecular Pathogenesis of Varicella-Zoster Virus Skin Lesions.

Arvin A Microbiol Mol Biol Rev. 2023; 87(3):e0011622.

PMID: 37354037 PMC: 10521358. DOI: 10.1128/mmbr.00116-22.

Humanized Severe Combined Immunodeficient (SCID) Mouse Models for Varicella-Zoster Virus Pathogenesis.

Lloyd M, Moffat J Curr Top Microbiol Immunol. 2022; 438:135-161.

PMID: 35292858 DOI: 10.1007/82_2022_255.

Manipulation of the Innate Immune Response by Varicella Zoster Virus.

Gerada C, Campbell T, Kennedy J, McSharry B, Steain M, Slobedman B Front Immunol. 2020; 11:1.

PMID: 32038653 PMC: 6992605. DOI: 10.3389/fimmu.2020.00001.

Varicella zoster virus productively infects human natural killer cells and manipulates phenotype.

Campbell T, McSharry B, Steain M, Ashhurst T, Slobedman B, Abendroth A PLoS Pathog. 2018; 14(4):e1006999.

PMID: 29709039 PMC: 5953475. DOI: 10.1371/journal.ppat.1006999.

Varicella zoster virus glycoprotein C increases chemokine-mediated leukocyte migration.

Gonzalez-Motos V, Jurgens C, Ritter B, Kropp K, Duran V, Larsen O PLoS Pathog. 2017; 13(5):e1006346.

PMID: 28542541 PMC: 5444840. DOI: 10.1371/journal.ppat.1006346.

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