Comprehensive Analysis of DNA Methylation Data with RnBeads

Overview

Journal Nat Methods

Specialties Biomedical Engineering
Pathology

Date 2014 Sep 29

PMID 25262207

Citations 359

Authors

Yassen Assenov

Fabian Muller

Pavlo Lutsik

Jorn Walter

Thomas Lengauer

Christoph Bock

Affiliations

Soon will be listed here.

Abstract

RnBeads is a software tool for large-scale analysis and interpretation of DNA methylation data, providing a user-friendly analysis workflow that yields detailed hypertext reports (http://rnbeads.mpi-inf.mpg.de/). Supported assays include whole-genome bisulfite sequencing, reduced representation bisulfite sequencing, Infinium microarrays and any other protocol that produces high-resolution DNA methylation data. Notable applications of RnBeads include the analysis of epigenome-wide association studies and epigenetic biomarker discovery in cancer cohorts.

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