Sheep (Ovis Aries) As a Model for Cardiovascular Surgery and Management Before, During, and After Cardiopulmonary Bypass

Overview

Journal J Am Assoc Lab Anim Sci

Date 2014 Sep 26

PMID 25255065

Citations 38

Authors

Louis DiVincenti Jr

Robin Westcott

Candice Lee

Affiliations

Soon will be listed here.

Abstract

Because of its similarity to humans in important respects, sheep (Ovis aries) are a common animal model for translational research in cardiovascular surgery. However, some unique aspects of sheep anatomy and physiology present challenges to its use in these complicated experiments. In this review, we discuss relevant anatomy and physiology of sheep and discuss management before, during, and after procedures requiring cardiopulmonary bypass to provide a concise source of information for veterinarians, technicians, and researchers developing and implementing protocols with this model.

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