Fungal Prosthetic Valve Endocarditis by Candida Parapsilosis: A Case Report

Overview

Journal Jundishapur J Microbiol

Publisher Brieflands

Specialty Microbiology

Date 2014 Aug 23

PMID 25147692

Citations 7

Authors

Tahereh Shokohi

Seyed Mahmood Nouraei

Mohammad Hosein Afsarian

Narges Najafi

Shirin Mehdipour

Affiliations

Soon will be listed here.

Abstract

Introduction: Fungal prosthetic valve endocarditis (PVE) is rare but serious complication of valve replacement surgery. Candida species, particularly Candida albicans is the most common isolated pathogen in fungal PVE (1-6%of cases).

Case Presentation: We describe a 35-year-old woman who underwent mechanical mitral valve replacement about 3 years ago. She was admitted with neurological symptoms and later with dyspnea and hypotension. Transesophageal echocardiography showed large and mobile prosthetic valve vegetation. She underwent mitral valve surgery. The explanted valve and vegetation revealed lots of budding yeasts and the isolated yeast was identified as C. parapsilosis. Amphotericin B and broad spectrum antibiotic were started immediately. Unfortunately, the patient died two days after surgery, due to sepsis probably related to the candidemia.

Conclusions: Fungal endocarditis is uncommon infection, but it is a serious problem in patients with prosthetic valve. Fungal PVE can occur years after the surgery, thus long-term follow-up is essential.

Citing Articles

Does Heart Failure Mask Candida Tricuspid Endocarditis?.

Mahmoud A, Khalid A, Ehle A, Kahf Y, Afzal A, Peltzer B Cureus. 2023; 15(5):e38951.

PMID: 37313062 PMC: 10259750. DOI: 10.7759/cureus.38951.

Native valve, prosthetic valve, and cardiac device-related infective endocarditis: A review and update on current innovative diagnostic and therapeutic strategies.

Kouijzer J, Noordermeer D, van Leeuwen W, Verkaik N, Lattwein K Front Cell Dev Biol. 2022; 10:995508.

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A case series of medically managed Candida parapsilosis complex prosthetic valve endocarditis.

Guo P, He Y, Fan R, Wu Z, Chen Y, Huang Y Ann Clin Microbiol Antimicrob. 2021; 20(1):1.

PMID: 33402178 PMC: 7786486. DOI: 10.1186/s12941-020-00409-4.

Fatal Prosthetic Valve Endocarditis Due to in a Diabetic Patient.

Jalalian R, Shokohi T, Mirzakhani R, Ghasemian R, Hedayati M, Ardalani S Infect Drug Resist. 2020; 13:2245-2250.

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Candida Endocarditis: A Review of the Pathogenesis, Morphology, Risk Factors, and Management of an Emerging and Serious Condition.

Mamtani S, Aljanabi N, Gupta Rauniyar R, Acharya A, Malik B Cureus. 2020; 12(1):e6695.

PMID: 32104631 PMC: 7026878. DOI: 10.7759/cureus.6695.

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