Association of Simple Anthropometric Indices and Body Fat with Early Atherosclerosis and Lipid Profiles in Chinese Adults

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2014 Aug 5

PMID 25090639

Citations 6

Authors

Zhe-Qing Zhang

Li-Ping He

Xiao-Yan Xie

Wen-Hua Ling

Juan Deng

Yi-Xiang Su

Yu-Ming Chen

Affiliations

Soon will be listed here.

Abstract

Objective: The discriminatory capability of different adiposity indices for atherosclerosis and lipid abnormalities remains uncertain. This study aimed to identify the best adiposity index for predicting early atherosclerosis and abnormal lipid profiles among anthropometric parameters and body fat measures in middle-aged and elderly Chinese.

Method: A total of 2,063 women and 814 men (57.6±5.2 y) were recruited for this community-based cross-sectional study. Body mass index (BMI), waist circumference (WC), hip circumference (HC), waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR) were assessed. Body fat mass and its percentage values for the whole body and trunk were measured by bioelectrical impedance analysis (BIA). The intima-media thicknesses (IMTs) of the common carotid arteries (CCA), internal carotid arteries (ICA) and bifurcation (BIF) were determined via B-mode ultrasound. The fasting lipid profiles were assessed.

Results: With per SD increase of adiposity indices, the magnitude of the changes of IMT values and lipid profiles was more substantial for WC, WHR and WHtR in both genders. A multivariate logistic regression analysis indicated that WC, WHR and WHtR were more sensitive in predicting the presence of intima-media thickening at the three segments as well as the lipids disturbances in women and men. In general, BIA-derived measures have no added predictive value for IMT-thickening as opposed to those three traditional abdominal measures.

Conclusion: Our findings suggest that abdominal anthropometric measures including WC, WHR and WHtR are sensitive for discriminating carotid atherosclerosis and lipids abnormalities. WC is the best index because of its simplicity in routine use.

Citing Articles

Independent Relevance of Different Measures of Adiposity for Carotid Intima-Media Thickness in 40 000 Adults in UK Biobank.

Pillay P, Carter J, Taylor H, Lewington S, Clarke R J Am Heart Assoc. 2023; 12(2):e026694.

PMID: 36625300 PMC: 9939056. DOI: 10.1161/JAHA.122.026694.

Associations between anthropometric parameters and lipid profiles in Chinese individuals with age ≥40 years and BMI <28kg/m2.

Yang Z, Ding X, Liu J, Duan P, Si L, Wan B PLoS One. 2017; 12(6):e0178343.

PMID: 28632766 PMC: 5478121. DOI: 10.1371/journal.pone.0178343.

Association of Neck Circumference with Obesity in Female College Students.

Papandreou D, Noor Z, Rashed M, Jaberi H Open Access Maced J Med Sci. 2016; 3(4):578-81.

PMID: 27275290 PMC: 4877890. DOI: 10.3889/oamjms.2015.118.

Associations of Body Composition Measurements with Serum Lipid, Glucose and Insulin Profile: A Chinese Twin Study.

Liao C, Gao W, Cao W, Lv J, Yu C, Wang S PLoS One. 2015; 10(11):e0140595.

PMID: 26556598 PMC: 4640552. DOI: 10.1371/journal.pone.0140595.

Association of Adiposity Indices with Platelet Distribution Width and Mean Platelet Volume in Chinese Adults.

Hou J, Liu C, Yao P, Chen W, He M, Wang Y PLoS One. 2015; 10(6):e0129677.

PMID: 26058081 PMC: 4461260. DOI: 10.1371/journal.pone.0129677.

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