WEB Intrasaccular Flow Disruptor-prospective, Multicenter Experience in 83 Patients with 85 Aneurysms

Overview

Journal AJNR Am J Neuroradiol

Specialty Neurology

Date 2014 Jul 5

PMID 24994823

Citations 59

Authors

C Papagiannaki

L Spelle

A-C Januel

A Benaissa

J-Y Gauvrit

V Costalat

H Desal

F Turjman

S Velasco

X Barreau

P Courtheoux

C Cognard

D Herbreteau

J Moret

L Pierot

Affiliations

Soon will be listed here.

Abstract

Background And Purpose: The safety and efficacy of WEB flow disruption have been analyzed in small, retrospective series. The object of this study was to evaluate the safety and efficacy of WEB flow disruption in a large, multicenter, prospectively collected population.

Materials And Methods: Data from all patients treated with the WEB-DL device between June 2011 and October 2013 in 11 French neurointerventional centers were prospectively collected and retrospectively analyzed. Complications occurring during and after treatment were analyzed as well as morbidity and mortality at 1 month. Aneurysm occlusion status at the last follow-up was analyzed.

Results: Eighty-three patients with 85 aneurysms were included in this series. Technical success was achieved in 77 patients with 79 aneurysms (92.9%). Periprocedural complications were observed in 9 patients (10.8%), leading to permanent neurologic deficits in 3 (3.9%). Morbidity and mortality at 1 month were 1.3% and 0.0%, respectively. Angiographic follow-up was performed for 65/79 aneurysms (82.3%) 3-24 months after treatment (mean, 5.3 months). Complete aneurysm occlusion was observed in 37/65 aneurysms (56.9%); neck remnant, in 23/65 (35.4%); and aneurysm remnant, in 5/65 (7.7%).

Conclusions: In this large prospective series of patients, WEB flow disruption was a safe and efficient technique.

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