Volatile Metabolites

Overview

Journal Metabolites

Publisher MDPI

Date 2014 Jun 25

PMID 24957243

Citations 37

Authors

Daryl D Rowan

Affiliations

Soon will be listed here.

Abstract

Volatile organic compounds (volatiles) comprise a chemically diverse class of low molecular weight organic compounds having an appreciable vapor pressure under ambient conditions. Volatiles produced by plants attract pollinators and seed dispersers, and provide defense against pests and pathogens. For insects, volatiles may act as pheromones directing social behavior or as cues for finding hosts or prey. For humans, volatiles are important as flavorants and as possible disease biomarkers. The marine environment is also a major source of halogenated and sulfur-containing volatiles which participate in the global cycling of these elements. While volatile analysis commonly measures a rather restricted set of analytes, the diverse and extreme physical properties of volatiles provide unique analytical challenges. Volatiles constitute only a small proportion of the total number of metabolites produced by living organisms, however, because of their roles as signaling molecules (semiochemicals) both within and between organisms, accurately measuring and determining the roles of these compounds is crucial to an integrated understanding of living systems. This review summarizes recent developments in volatile research from a metabolomics perspective with a focus on the role of recent technical innovation in developing new areas of volatile research and expanding the range of ecological interactions which may be mediated by volatile organic metabolites.

Citing Articles

Phytochemical Insights and Therapeutic Potential of and .

Kozhantayeva A, Iskakova Z, Ibrayeva M, Sapiyeva A, Arkharbekova M, Tashenov Y Molecules. 2025; 30(5).

PMID: 40076409 PMC: 11901623. DOI: 10.3390/molecules30051186.

Exposure to Volatile Organic Compounds in Relation to Visceral Adiposity Index and Lipid Accumulation Product Among U.S. Adults: NHANES 2011-2018.

Qian Z, Dai C, Chen S, Yang L, Huo X Toxics. 2025; 13(1).

PMID: 39853044 PMC: 11768580. DOI: 10.3390/toxics13010046.

Analysis of Plant Volatiles Using Active Sampling and TD-GC×GC-TOFMS.

Schmidt S, Mesfin E, Weeraddana C, de la Mata A, Costamagna A, Harynuk J Metabolites. 2024; 14(11).

PMID: 39590859 PMC: 11596084. DOI: 10.3390/metabo14110623.

Ammonia leakage can underpin nitrogen-sharing among soil microorganisms.

Richards L, Cremin K, Coates M, Vigor F, Schafer P, Soyer O ISME J. 2024; 18(1).

PMID: 39236233 PMC: 11440039. DOI: 10.1093/ismejo/wrae171.

Volatile Organic Compound Metabolism on Early Earth.

Ledford S, Meredith L J Mol Evol. 2024; 92(5):605-617.

PMID: 39017923 PMC: 11458752. DOI: 10.1007/s00239-024-10184-x.

References

McKenzie M, Hunter D, Pathirana R, Watson L, Joyce N, Matich A . Accumulation of an organic anticancer selenium compound in a transgenic Solanaceous species shows wider applicability of the selenocysteine methyltransferase transgene from selenium hyperaccumulators. Transgenic Res. 2008; 18(3):407-24. DOI: 10.1007/s11248-008-9233-0. View

Beranek J, Kubatova A . Evaluation of solid-phase microextraction methods for determination of trace concentration aldehydes in aqueous solution. J Chromatogr A. 2008; 1209(1-2):44-54. DOI: 10.1016/j.chroma.2008.09.013. View

Dudareva N, Negre F . Practical applications of research into the regulation of plant volatile emission. Curr Opin Plant Biol. 2005; 8(1):113-8. DOI: 10.1016/j.pbi.2004.11.007. View

Schauer N, Zamir D, Fernie A . Metabolic profiling of leaves and fruit of wild species tomato: a survey of the Solanum lycopersicum complex. J Exp Bot. 2004; 56(410):297-307. DOI: 10.1093/jxb/eri057. View

Banuelos G, Lin Z, Wu L, Terry N . Phytoremediation of selenium-contaminated soils and waters: fundamentals and future prospects. Rev Environ Health. 2003; 17(4):291-306. DOI: 10.1515/reveh.2002.17.4.291. View

Stewart D, McDougall G, Sungurtas J, Verrall S, Graham J, Martinussen I . Metabolomic approach to identifying bioactive compounds in berries: advances toward fruit nutritional enhancement. Mol Nutr Food Res. 2007; 51(6):645-51. DOI: 10.1002/mnfr.200700056. View

Vuckovic D, Risticevic S, Pawliszyn J . In vivo solid-phase microextraction in metabolomics: opportunities for the direct investigation of biological systems. Angew Chem Int Ed Engl. 2011; 50(25):5618-28. DOI: 10.1002/anie.201006896. View

Rasulov B, Huve K, Laisk A, Niinemets U . Induction of a longer term component of isoprene release in darkened aspen leaves: origin and regulation under different environmental conditions. Plant Physiol. 2011; 156(2):816-31. PMC: 3177278. DOI: 10.1104/pp.111.176222. View

Dicke M, van Loon J, Soler R . Chemical complexity of volatiles from plants induced by multiple attack. Nat Chem Biol. 2009; 5(5):317-24. DOI: 10.1038/nchembio.169. View

10.

Rasulov B, Huve K, Bichele I, Laisk A, Niinemets U . Temperature response of isoprene emission in vivo reflects a combined effect of substrate limitations and isoprene synthase activity: a kinetic analysis. Plant Physiol. 2010; 154(3):1558-70. PMC: 2971629. DOI: 10.1104/pp.110.162081. View

11.

Kegge W, Pierik R . Biogenic volatile organic compounds and plant competition. Trends Plant Sci. 2009; 15(3):126-32. DOI: 10.1016/j.tplants.2009.11.007. View

12.

Rowan D, Hunt M, Dimouro A, Alspach P, Weskett R, Volz R . Profiling fruit volatiles in the progeny of a 'Royal Gala' x 'Granny Smith' apple (Malus x domestica) cross. J Agric Food Chem. 2009; 57(17):7953-61. DOI: 10.1021/jf901678v. View

13.

Soini H, Wiesler D, Koyama S, Feron C, Baudoin C, Novotny M . Comparison of urinary scents of two related mouse species, Mus spicilegus and Mus domesticus. J Chem Ecol. 2009; 35(5):580-9. DOI: 10.1007/s10886-009-9628-2. View

14.

Dandurishvili N, Toklikishvili N, Ovadis M, Eliashvili P, Giorgobiani N, Keshelava R . Broad-range antagonistic rhizobacteria Pseudomonas fluorescens and Serratia plymuthica suppress Agrobacterium crown gall tumours on tomato plants. J Appl Microbiol. 2010; 110(1):341-52. DOI: 10.1111/j.1365-2672.2010.04891.x. View

15.

Dickschat J, Zell C, Brock N . Pathways and substrate specificity of DMSP catabolism in marine bacteria of the Roseobacter clade. Chembiochem. 2010; 11(3):417-25. DOI: 10.1002/cbic.200900668. View

16.

Rowan D, Hunt M, Alspach P, Whitworth C, Oraguzie N . Heritability and genetic and phenotypic correlations of apple (Malus x domestica) fruit volatiles in a genetically diverse breeding population. J Agric Food Chem. 2009; 57(17):7944-52. DOI: 10.1021/jf901359r. View

17.

Faulkner D . Marine natural products. Nat Prod Rep. 2002; 19(1):1-48. DOI: 10.1039/b009029h. View

18.

Basanta M, Jarvis R, Xu Y, Blackburn G, Tal-Singer R, Woodcock A . Non-invasive metabolomic analysis of breath using differential mobility spectrometry in patients with chronic obstructive pulmonary disease and healthy smokers. Analyst. 2010; 135(2):315-20. DOI: 10.1039/b916374c. View

19.

Bentley R, Chasteen T . Environmental VOSCs--formation and degradation of dimethyl sulfide, methanethiol and related materials. Chemosphere. 2004; 55(3):291-317. DOI: 10.1016/j.chemosphere.2003.12.017. View

20.

Marko G, Novak I, Bernath J, Altbacker V . Both gas chromatography and an electronic nose reflect chemical polymorphism of juniper shrubs browsed or avoided by sheep. J Chem Ecol. 2011; 37(7):705-13. DOI: 10.1007/s10886-011-9974-8. View