Myxochelin A, a New Iron-chelating Compound from Angiococcus Disciformis (Myxobacterales). Production, Isolation, Physico-chemical and Biological Properties

Overview

Journal J Antibiot (Tokyo)

Specialties Infectious Diseases
Pharmacology

Date 1989 Jan 1

PMID 2493439

Citations 29

Authors

B Kunze

N Bedorf

W Kohl

G Hofle

H Reichenbach

Affiliations

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Abstract

Myxochelin A, a new catechole siderophore, was isolated from the culture broth of the myxobacterium, Angiococcus disciformis strain An d30. As is the case with other iron-chelating compounds the production of myxochelin A could be markedly increased up to 44 mg/liter by fermentation at low iron concentrations (10(-7) M FeCl3). The new substance showed weak activity against some bacteria.

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