Intratypic Heterologous Vaccination of Calves Can Induce an Antibody Response in Presence of Maternal Antibodies Against Foot-and-mouth Disease Virus

Overview

Journal BMC Vet Res

Publisher Biomed Central

Specialty Veterinary Medicine

Date 2014 Jun 8

PMID 24906852

Citations 5

Authors

Aldo Dekker

Phaedra Eble

Norbert Stockhofe

Gilles Chenard

Affiliations

Soon will be listed here.

Abstract

Background: Maternal antibodies can interfere with foot-and-mouth disease vaccination. In this study we determined whether intratypic heterologous vaccination could help to improve herd immunity.

Results: In unvaccinated calves, a half-life of maternal antibodies of 21 days was determined. At two weeks of age, calves without maternal antibodies showed a good antibody response against both vaccines used in the trial, while in calves with maternal antibodies no antibody response to homologous vaccination (A Turkey 14/98) but a limited antibody response to intratypic heterologous vaccination (A22 Iraq) was observed.

Conclusion: Two weeks old calves without maternal antibodies respond well to vaccination, but when emergency vaccination is carried out in a region that uses prophylactic vaccination, using an intratypic heterologous vaccine strain may improve the immunity in calves with maternal antibodies.

Citing Articles

Maternally Derived Antibodies to Foot-and-Mouth Disease Virus Modulate the Antigenic Specificity of Humoral Responses in Vaccinated Cattle.

Senawi J, Wilsden G, Browning C, Ludi A, Ismail M, Senin H Vaccines (Basel). 2023; 11(12).

PMID: 38140247 PMC: 10747493. DOI: 10.3390/vaccines11121844.

Risk factors for the incursion, spread and persistence of the foot and mouth disease virus in Eastern Rwanda.

Udahemuka J, Aboge G, Obiero G, Lebea P, Onono J, Paone M BMC Vet Res. 2020; 16(1):387.

PMID: 33046049 PMC: 7552508. DOI: 10.1186/s12917-020-02610-1.

Foot-and-Mouth Disease Virus: Immunobiology, Advances in Vaccines and Vaccination Strategies Addressing Vaccine Failures-An Indian Perspective.

Singh R, Sharma G, Mahajan S, Dhama K, Basagoudanavar S, Hosamani M Vaccines (Basel). 2019; 7(3).

PMID: 31426368 PMC: 6789522. DOI: 10.3390/vaccines7030090.

Influence of vaccine potency and booster administration of foot-and-mouth disease vaccines on the antibody response in calves with maternal antibodies.

Cokcaliskan C, Turkoglu T, Uzunlu E, Sareyyupoglu B, Hanci I, Ipek A J Vet Sci. 2017; 18(S1):315-322.

PMID: 28859271 PMC: 5583419. DOI: 10.4142/jvs.2017.18.S1.315.

Proper Timing of Foot-and-Mouth Disease Vaccination of Piglets with Maternally Derived Antibodies Will Maximize Expected Protection Levels.

Dekker A, Chenard G, Stockhofe N, Eble P Front Vet Sci. 2016; 3:52.

PMID: 27446940 PMC: 4927624. DOI: 10.3389/fvets.2016.00052.

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