Subclinical Celiac Disease and Gluten Sensitivity

Overview

Journal Gastroenterol Hepatol Bed Bench

Specialty Gastroenterology

Date 2014 May 17

PMID 24834166

Citations 22

Authors

Mohammad Rostami Nejad

Sabine Hogg-Kollars

Sauid Ishaq

Kamran Rostami

Affiliations

Soon will be listed here.

Abstract

Atypical presentation is the most common form of celiac disease (CD). Although the terminologies like latent, silent and potential have expressed different aspects of clinical and pathological behaviour of CD, they also have contributed in some extent to confusion between clinicians and patients due to the multiple definitions and uncertainty around them. In the light of new advances and the discovery of entities such as non-celiac gluten sensitivity, using subclinical instead of silent and atypical instead of potential/latent may simplify the understanding behind the clinical behaviour of atypical CD. The evidence behind a lower threshold for starting a gluten free diet (GFD) in non-celiac gluten sensitive patients would strongly support applying a GFD treatment strategy in any forms of CD.

Citing Articles

Is duodenal biopsy always necessary for the diagnosis of coeliac disease in adult patients with high anti-tissue transglutaminase (TTG) antibody titres?.

Beig J, Rostami K, Hayman D, Hassan S, Gerred S, Ogra R Frontline Gastroenterol. 2022; 13(4):287-294.

PMID: 35722610 PMC: 9186042. DOI: 10.1136/flgastro-2020-101728.

Prevalence of celiac disease in low and high risk population in Asia-Pacific region: a systematic review and meta-analysis.

Ashtari S, Najafimehr H, Pourhoseingholi M, Rostami K, Asadzadeh-Aghdaei H, Rostami-Nejad M Sci Rep. 2021; 11(1):2383.

PMID: 33504878 PMC: 7841177. DOI: 10.1038/s41598-021-82023-8.

An updated overview of spectrum of gluten-related disorders: clinical and diagnostic aspects.

Taraghikhah N, Ashtari S, Asri N, Shahbazkhani B, Al-Dulaimi D, Rostami-Nejad M BMC Gastroenterol. 2020; 20(1):258.

PMID: 32762724 PMC: 7409416. DOI: 10.1186/s12876-020-01390-0.

The effects of IL-8, IL- 6, and IL-1 on the risk of celiac disease: a Bayesian regression analysis.

Nasserinejad M, Shojaee S, Ghobakhlou M, Lak E, Eslami P, Pourhoseingholi M Gastroenterol Hepatol Bed Bench. 2020; 12(Suppl1):S117-S122.

PMID: 32099611 PMC: 7011063.

Comparison of cytokine and gene activities in tissue and blood samples of patients with celiac disease.

Khalkhal E, Razzaghi Z, Zali H, Bahadorimonfared A, Iranshahi M, Rostami-Nejad M Gastroenterol Hepatol Bed Bench. 2020; 12(Suppl1):S108-S116.

PMID: 32099610 PMC: 7011060.

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