Cutaneous and Mucosal Manifestations Associated with Celiac Disease

Overview

Journal Nutrients

Date 2018 Jun 24

PMID 29933630

Citations 31

Authors

Luis Rodrigo

Valia Beteta-Gorriti

Nuria Alvarez

Celia Gomez de Castro

Alvaro de Dios

Laura Palacios

Jorge Santos-Juanes

Affiliations

Soon will be listed here.

Abstract

Celiac disease (CD) is an immune-mediated, gluten-induced enteropathy that affects predisposed individuals of all ages. Many patients with CD do not report gastrointestinal symptoms making it difficult to reach an early diagnosis. On the other hand, CD is related to a wide spectrum of extra-intestinal manifestations, with dermatitis herpetiformis (DH) being the best characterized. These associated conditions may be the clue to reaching the diagnosis of CD. Over the last few years, there have been multiple reports of the association between CD and several cutaneous manifestations that may improve with a gluten-free diet (GFD). The presence of some of these skin diseases, even in the absence of gastrointestinal symptoms, should give rise to an appropriate screening method for CD. The aim of this paper is to describe the different cutaneous manifestations that have been associated with CD and the possible mechanisms involved.

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