Spinal Dissemination of Intracranial Glioblastoma in Bevacizumab Era: a Potential Bevacizumab-induced Mechanism

Overview

Journal Acta Inform Med

Specialty General Medicine

Date 2014 May 15

PMID 24825943

Citations 1

Authors

Gentian Kaloshi

Arben Roji

Arsen Seferi

Bujar Cakani

Teona Bushati

Ermir Roci

Mentor Petrela

Affiliations

Soon will be listed here.

Abstract

Spinal metastasis, a devastating neurologic complication of intracranial glioblastomas is not as uncommon as initially thought. It varies from 25% in supratentorial glioblastomas to 60% in infratentorial glioblastomas. The underlying pathogenesis spinal spread of high-grade gliomas is still unclear. To date, no causal responsibility of Bevacizumab (BEV) was noted. Here, we report for the first time, a case of thoracic intramedullary metastases from a cerebral glioblastoma pre-treated with BEV. A critical and exhaustive review is provided.

Citing Articles

Leptomeningeal Spread in Glioblastoma: Diagnostic and Therapeutic Challenges.

Birzu C, Tran S, Bielle F, Touat M, Mokhtari K, Younan N Oncologist. 2021; 25(11):e1763-e1776.

PMID: 33394574 PMC: 7648332. DOI: 10.1634/theoncologist.2020-0258.

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