Metal-free Oxidative Synthesis of Quinazolinones Via Dual Amination of Sp3 C-H Bonds

Overview

Journal Chem Commun (Camb)

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2014 May 13

PMID 24816567

Citations 10

Authors

Dan Zhao

Teng Wang

Jian-Xin Li

Affiliations

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Abstract

A novel metal-free synthesis of quinazolinones via dual amination of sp(3) C-H bonds was developed. The sp(3) carbon in methylarenes or adjacent to a heteroatom in DMSO, DMF or DMA was used as the one carbon synthon.

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