Four New Jacaranone Analogs from the Fruits of a Beibu Gulf Mangrove Avicennia Marina

Overview

Journal Mar Drugs

Publisher MDPI

Specialties Biology
Pharmacology

Date 2014 May 7

PMID 24796307

Citations 7

Authors

Xiang-Xi Yi

Yong Chen

Wen-Pei Xie

Ming-Ben Xu

Yin-Ning Chen

Cheng-Hai Gao

Ri-Ming Huang

Affiliations

Soon will be listed here.

Abstract

Four new jacaranone analogs, marinoids F-I (1-4), were isolated from the fruits of a Beibu Gulf mangrove Avicennia marina. The structures were elucidated based on analysis of spectroscopic data. Marinoids F and G are shown to be diastereoisomers of chlorocornoside, a new halogen containing marine secondary metabolite. The antioxidant activity of the isolates was evaluated using a cellular antioxidant assay, and 4 showed good antioxidant activity (EC₅₀ = 26 μM).

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