Selective Inhibition by Vasocortin of Histamine Release Induced by Dextran and Concanavalin-A from Rat Peritoneal Cells
Overview
Overview
Journal
Br J Pharmacol
Publisher
Wiley
Specialty
Pharmacology
Date
1989 Sep 1
PMID
2478246
Citations
1
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Abstract
Vasocortin, a glucocorticoid-induced anti-inflammatory protein, has been purified from the peritoneal lavage fluid of dexamethasone-treated rats. Vasocortin inhibited the release of histamine from rat peritoneal cells stimulated by dextran or concanavalin A but did not alter the release induced by calcium ionophore A23187 or compound 48/80. This selective effect exhibited by vasocortin mimics the glucocorticoid inhibition of histamine release from rat mast cells.
Citing Articles
Sautebin L, Cirino G, Rosa M Mediators Inflamm. 1992; 1(4):251-4.
PMID: 18475469 PMC: 2365348. DOI: 10.1155/S0962935192000383.
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