DNA----DNA, and DNA----RNA----protein: Orchestration by a Single Complex Operon
Overview
Cell Biology
Molecular Biology
Authors
Affiliations
In Escherichia coli, the workhorse of molecular biology, a single operon is involved in the replication, transcription and translation of genetic information. This operon is controlled in a complex manner involving multiple cis-acting regulatory sequences and trans-acting regulatory proteins. It interacts with global regulatory networks by mechanisms which are presently being dissected.
Quantitation of the ribosomal protein autoregulatory network using mass spectrometry.
Sykes M, Sperling E, Chen S, Williamson J Anal Chem. 2010; 82(12):5038-45.
PMID: 20481440 PMC: 2894367. DOI: 10.1021/ac9028664.
Connected gene neighborhoods in prokaryotic genomes.
Rogozin I, Makarova K, Murvai J, Czabarka E, Wolf Y, Tatusov R Nucleic Acids Res. 2002; 30(10):2212-23.
PMID: 12000841 PMC: 115289. DOI: 10.1093/nar/30.10.2212.
Klann A, Belanger A, Lee J, Hatfull G J Bacteriol. 1998; 180(1):65-72.
PMID: 9422594 PMC: 106850. DOI: 10.1128/JB.180.1.65-72.1998.
Transcriptional characterization of the Rickettsia prowazekii major macromolecular synthesis operon.
SHAW E, Marks G, Winkler H, Wood D J Bacteriol. 1997; 179(20):6448-52.
PMID: 9335295 PMC: 179562. DOI: 10.1128/jb.179.20.6448-6452.1997.
Grompe M, Versalovic J, Koeuth T, Lupski J J Bacteriol. 1991; 173(3):1268-78.
PMID: 1991720 PMC: 207251. DOI: 10.1128/jb.173.3.1268-1278.1991.