Reference Equations for 6-min Walk Test in Healthy Indian Subjects (25-80 Years)

Overview

Journal Lung India

Specialty Pulmonary Medicine

Date 2014 Mar 27

PMID 24669079

Citations 16

Authors

Ramanathan Palaniappan Ramanathan

Baskaran Chandrasekaran

Affiliations

Soon will be listed here.

Abstract

Background: Six-min walk test (6MWT), a simple functional capacity evaluation tool used globally to determine the prognosis and effectiveness of any therapeutic/medical intervention. However, variability in reference equations derived from western population (due to racial and ethnicity variations) hinders from adequate use of 6MWT clinically. Further, there are no valid Indian studies that predict reference values for 6-min walk distance (6MWD) in healthy Indian normal.

Objective: We aimed for framing individualized reference equations for 6MWT in healthy Indian population.

Materials And Methods: Anthropometric variables (age, weight, height, and body mass index (BMI)) and 6-min walk in a 30 m corridor were evaluated in 125 subjects (67 females) in a cross-sectional trial.

Results: 6MWD significantly correlated with age (r = -0.29), height (r = 0.393), weight (r = 0.08), and BMI (r = -0.17). The gender specific reference equations for healthy Indian individuals were: (1) Males: 561.022 - (2.507 × age [years]) + (1.505 × weight [kg]) - (0.055 × height [cm]). R (2) = 0.288. (2) Indian females: 30.325 - (0.809 × age [years]) - (2.074 × weight [kg]) + (4.235 × height [cm]). R (2) = 0.272. Though the equations possess a small coefficient of determination and larger standard error estimate, the former applicability to Indian population is justified.

Conclusion: These reference equations are probably most appropriate for evaluating the walked capacity of Indian patients with chronic diseases.

Citing Articles

The Assessment of Functional Status Among COVID-19 Patients at Three Months Using Pulmonary Function Tests.

Asija M, Dahiya S, Parsad R, Fotedar S, Sharma R, Bhatthi V Cureus. 2024; 16(5):e61221.

PMID: 38939290 PMC: 11209644. DOI: 10.7759/cureus.61221.

Effect of home-based pulmonary rehabilitation on exercise capacity in post COVID-19 patients: a randomized controlled trail.

Abo Elyazed T, Alsharawy L, Salem S, Helmy N, Abd El-Hakim A J Neuroeng Rehabil. 2024; 21(1):40.

PMID: 38528512 PMC: 10964649. DOI: 10.1186/s12984-024-01340-x.

Impact of HRCT pattern on six-minute walk test in patients with interstitial lung disease-An observational study.

Saxena P, Singh I, Kumar A, Kartik S, Malik V, Tiwari S Lung India. 2023; 40(5):429-433.

PMID: 37787356 PMC: 10553773. DOI: 10.4103/lungindia.lungindia_165_23.

Reference standards for the 6-min walk test in Croatian older adults.

Sagat P Front Physiol. 2023; 14:1226585.

PMID: 37601636 PMC: 10436743. DOI: 10.3389/fphys.2023.1226585.

Predictive equation for six-minute walk test in Indian children, adolescents, and adults.

Agarwal B, Shah M, Sawant B, Bagwe H, Murkudkar P, Mullerpatan R Lung India. 2023; 40(2):143-148.

PMID: 37006098 PMC: 10174647. DOI: 10.4103/lungindia.lungindia_680_21.

References

Sivaranjini S, Vanamail P, Eason J . Six minute walk test in people with tuberculosis sequelae. Cardiopulm Phys Ther J. 2010; 21(3):5-10. PMC: 2941351. View

Camarri B, Eastwood P, Cecins N, Thompson P, Jenkins S . Six minute walk distance in healthy subjects aged 55-75 years. Respir Med. 2005; 100(4):658-65. DOI: 10.1016/j.rmed.2005.08.003. View

Kervio G, Carre F, Ville N . Reliability and intensity of the six-minute walk test in healthy elderly subjects. Med Sci Sports Exerc. 2003; 35(1):169-74. DOI: 10.1097/00005768-200301000-00025. View

. ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002; 166(1):111-7. DOI: 10.1164/ajrccm.166.1.at1102. View

Enright P, McBurnie M, Bittner V, Tracy R, McNamara R, Arnold A . The 6-min walk test: a quick measure of functional status in elderly adults. Chest. 2003; 123(2):387-98. DOI: 10.1378/chest.123.2.387. View

Chetta A, Zanini A, Pisi G, Aiello M, Tzani P, Neri M . Reference values for the 6-min walk test in healthy subjects 20-50 years old. Respir Med. 2006; 100(9):1573-8. DOI: 10.1016/j.rmed.2006.01.001. View

Casanova C, Celli B, Barria P, Casas A, Cote C, de Torres J . The 6-min walk distance in healthy subjects: reference standards from seven countries. Eur Respir J. 2010; 37(1):150-6. DOI: 10.1183/09031936.00194909. View

Poh H, Eastwood P, Cecins N, Ho K, Jenkins S . Six-minute walk distance in healthy Singaporean adults cannot be predicted using reference equations derived from Caucasian populations. Respirology. 2006; 11(2):211-6. DOI: 10.1111/j.1440-1843.2006.00820.x. View

Troosters T, Gosselink R, Decramer M . Six minute walking distance in healthy elderly subjects. Eur Respir J. 1999; 14(2):270-4. DOI: 10.1034/j.1399-3003.1999.14b06.x. View

10.

Meyer F, Borst M, Buschmann H, Ewert R, Friedmann-Bette B, Ochmann U . [Exercise testing in respiratory medicine]. Pneumologie. 2013; 67(1):16-34. DOI: 10.1055/s-0032-1325901. View

11.

Iwama A, Andrade G, Shima P, Tanni S, Godoy I, Dourado V . The six-minute walk test and body weight-walk distance product in healthy Brazilian subjects. Braz J Med Biol Res. 2009; 42(11):1080-5. DOI: 10.1590/s0100-879x2009005000032. View

12.

Ross R, Murthy J, Wollak I, Jackson A . The six minute walk test accurately estimates mean peak oxygen uptake. BMC Pulm Med. 2010; 10:31. PMC: 2882364. DOI: 10.1186/1471-2466-10-31. View