Ecology and Metabolism of the Beneficial Intestinal Commensal Bacterium Faecalibacterium Prausnitzii

Overview

Journal Gut Microbes

Specialties Gastroenterology
Microbiology

Date 2014 Mar 19

PMID 24637606

Citations 83

Authors

Sylvie Miquel

Rebeca Martin

Chantal Bridonneau

Veronique Robert

Harry Sokol

Luis G Bermudez-Humaran

Muriel Thomas

Philippe Langella

Affiliations

Soon will be listed here.

Abstract

Faecalibacterium prausnitzii is a major commensal bacterium, and its prevalence is often decreased in conditions of intestinal dysbiosis. The phylogenic identity of this bacterium was described only recently. It is still poorly characterized, and its specific growth requirements in the human gastrointestinal tract are not known. In this review, we consider F. prausnitzii metabolism, its ecophysiology in both humans and animals, and the effects of drugs and nutrition on its population. We list important questions about this beneficial and ubiquitous commensal bacterium that it would be valuable to answer.

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