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Super-resolution Imaging with Stochastic Single-molecule Localization: Concepts, Technical Developments, and Biological Applications

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Specialty Radiology
Date 2014 Mar 12
PMID 24616244
Citations 15
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Abstract

Light microscopy has undergone a revolution with the advent of super-resolution microscopy methods that can surpass the diffraction limit. These methods have generated much enthusiasm, in particular with regards to the new possibilities they offer for biological imaging. The recent years have seen a great advancement both in terms of new technological developments and exciting biological applications. Here, we review some of the important milestones in the field and highlight some recent biological applications.

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