Hyperphagia: Current Concepts and Future Directions Proceedings of the 2nd International Conference on Hyperphagia

Overview

Journal Obesity (Silver Spring)

Specialties Endocrinology
Nutritional Sciences
Physiology

Date 2014 Feb 28

PMID 24574081

Citations 48

Authors

Steven B Heymsfield

Nicole M Avena

Leslie Baier

Phillip Brantley

George A Bray

Lisa C Burnett

Merlin G Butler

Daniel J Driscoll

Dieter Egli

Joel Elmquist

Janice L Forster

Anthony P Goldstone

Linda M Gourash

Frank L Greenway

Joan C Han

James G Kane

Rudolph L Leibel

Ruth J F Loos

Ann O Scheimann

Christian L Roth

Randy J Seeley

Val Sheffield

Maithe Tauber

Christian Vaisse

Liheng Wang

Robert A Waterland

Rachel Wevrick

Jack A Yanovski

Andrew R Zinn

Affiliations

Soon will be listed here.

Abstract

Objective: Hyperphagia is a central feature of inherited disorders (e.g., Prader-Willi Syndrome) in which obesity is a primary phenotypic component. Hyperphagia may also contribute to obesity as observed in the general population, thus raising the potential importance of common underlying mechanisms and treatments. Substantial gaps in understanding the molecular basis of inherited hyperphagia syndromes are present as are a lack of mechanistic of mechanistic targets that can serve as a basis for pharmacologic and behavioral treatments.

Design And Methods: International conference with 28 experts, including scientists and caregivers, providing presentations, panel discussions, and debates.

Results: The reviewed collective research and clinical experience provides a critical body of new and novel information on hyperphagia at levels ranging from molecular to population. Gaps in understanding and tools needed for additional research were identified.

Conclusions: This report documents the full scope of important topics reviewed at a comprehensive international meeting devoted to the topic of hyperphagia and identifies key areas for future funding and research.

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