Assessment of Liver Fat in an Obese Patient Population Using Noncontrast CT Fat Percent Index

Overview

Journal Clin Imaging

Publisher Elsevier

Specialty Radiology

Date 2014 Feb 25

PMID 24559751

Authors

Ali F Jon

Ahmad R Cheema

Atif N Khan

Vassilios Raptopoulos

Thomas Hauser

Imad Nasser

Francine K Welty

Andrew Karellas

Melvin E Clouse

Affiliations

Soon will be listed here.

Abstract

Objective: To develop a simplified method to quantify liver fat using computed tomography (CT) fat % index (CTFPI) compared to liver spleen method (CTL/S, CTL-S).

Methods: Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CTFPI=[(65-patient HU)/65]×100, normal live r=65 HU.

Results: There was a strong linear correlation between CTFPI and the standard method of assessing liver fat using CTL/S (r=-0.901), CTL-S (r=-0.911). Hepatic HU and CTFPI were significantly different in the severely obese group compared to other two groups (P<.05).

Conclusion: Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.

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