Using Fiducial Markers in the Prostate Bed in Postprostatectomy External Beam Radiation Therapy Improves Accuracy over Surgical Clips

Overview

Journal Strahlenther Onkol

Specialties Oncology
Radiology

Date 2014 Feb 22

PMID 24557058

Citations 11

Authors

I Fortin

J-F Carrier

M-C Beauchemin

D Beliveau-Nadeau

G Delouya

D Taussky

Affiliations

Soon will be listed here.

Abstract

Background And Purpose: The purpose of this work was to assess the stability of fiducial markers in the prostate bed and compared their use to surgical clips.

Patients And Methods: In this study, 3-4 gold fiducial markers were transrectally implanted in the prostate bed of 14 patients. The stability of the fiducial markers position (fiducial markers fixity) over an EBRT course was assessed. Furthermore, the advantages of the fiducial markers compared to the surgical clips were assessed and the interobserver variation between the two technologies was compared.

Results: The mean fiducial marker migration during a course of EBRT was small with 1.2 mm (SD ± 0.8 mm). Compared to fiducial markers, the matches with surgical clips were mismatched ≥ 2 mm in 68% of treatments. This discrepancy of > 2 mm was on average 3.7 ± 1.3 mm. There was less interobserver variability for matching of fiducial markers (0.8 ± 0.7 mm) than for surgical clips (2.0 ± 1.6 mm).

Conclusion: Fiducial markers showed less interobserver variability in matching and less variation in position than surgical clips. Fiducial markers could ultimately help in reducing treatment margins.

Citing Articles

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PMID: 33898783 PMC: 8058020. DOI: 10.1016/j.phro.2021.01.008.

The use of tissue fiducial markers in improving the accuracy of post-prostatectomy radiotherapy.

Chao M, Ho H, Joon D, Chan Y, Spencer S, Ng M Radiat Oncol J. 2019; 37(1):43-50.

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Does Interfraction Cone Beam Computed Tomography Improve Target Localization in Prostate Bed Radiotherapy?.

Elakshar S, Tsui J, Kucharczyk M, Tomic N, Fawaz Z, Bahoric B Technol Cancer Res Treat. 2019; 18:1533033819831962.

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Fiducial markers: can the urologist do better?.

Duncan C, Joon D, Lawrentschuk N, Jenkins T, Schneider M, Khoo V World J Urol. 2018; 37(7):1281-1287.

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Dobiasch S, Kampfer S, Burkhardt R, Schilling D, Schmid T, Wilkens J Strahlenther Onkol. 2017; 193(12):1039-1047.

PMID: 28808749 DOI: 10.1007/s00066-017-1193-y.

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