Experimental Realization of Fluence Field Modulated CT Using Digital Beam Attenuation
Overview
Nuclear Medicine
Radiology
Authors
Affiliations
Tailoring CT scan acquisition parameters to individual patients is a topic of much research in the CT imaging community. It is now common place to find automatically adjusted tube current options for modern CT scanners. In addition, the use of beam shaping filters, commonly called bowtie filters, is available on most CT systems and allows for different body regions to receive different incident x-ray fluence distributions. However, no method currently exists which allows for the form of the incident x-ray fluence distribution to change as a function of the view angle. This study represents the first experimental realization of fluence field modulated CT (FFMCT) for a c-arm geometry CT scan. X-ray fluence modulation is accomplished using a digital beam attenuator (DBA). The device is composed of ten iron wedge pairs that modulate the thickness of iron, the x-rays must traverse before reaching a patient. Using this device, experimental data was taken using a Siemens Zeego c-arm scanner. Scans were performed on a cylindrical polyethylene phantom and on two different sections of an anthropomorphic phantom. The DBA was used to equalize the x-ray fluence striking the detector for each scan. Non DBA, or 'flat field' scans were also acquired of the same phantom objects for comparison. In addition, a scan was performed in which the DBA was used to enable volume of interest (VOI) imaging. In VOI, only a small sub-volume within a patient receives full dose and the rest of the patient receives a much lower dose. Data corrections unique to using a piece-wise constant modulator were also developed. The feasibility of FFMCT implemented using a DBA device has been demonstrated. Initial results suggest dose reductions of up to 3.6 times relative to 'flat field' CT. In addition to dose reduction, the DBA enables a large improvement in image noise uniformity and the ability to provide regionally enhanced signal to noise using VOI imaging techniques. The results presented in this paper take the field of FFMCT from the theoretical stage to that of possible clinical implementation. FFMCT, as shown in this paper, can reduce the patient dose while maintaining or improving image quality. In addition, the DBA has been experimentally shown to be well suited to implement entirely new imaging methods like photon counting and VOI imaging.
Jacobsen M, Thrower S, Ger R, Leng S, Court L, Brock K Med Phys. 2020; 47(8):3752-3771.
PMID: 32453879 PMC: 8495770. DOI: 10.1002/mp.14241.
Dynamic fluence field modulation in computed tomography using multiple aperture devices.
Gang G, Mao A, Wang W, Siewerdsen J, Mathews A, Kawamoto S Phys Med Biol. 2019; 64(10):105024.
PMID: 30939459 PMC: 6897305. DOI: 10.1088/1361-6560/ab155e.
Implementation and Assessment of Dynamic Fluence Field Modulation with Multiple Aperture Devices.
Gang G, Mao A, Siewerdsen J, Stayman J Conf Proc Int Conf Image Form Xray Comput Tomogr. 2018; 2018:47-51.
PMID: 30506056 PMC: 6261319.
Dynamic fluence field modulation for miscentered patients in computed tomography.
Mao A, Gang G, Shyr W, Levinson R, Siewerdsen J, Kawamoto S J Med Imaging (Bellingham). 2018; 5(4):043501.
PMID: 30397631 PMC: 6199669. DOI: 10.1117/1.JMI.5.4.043501.
Quantitative accuracy of CT numbers: Theoretical analyses and experimental studies.
Zhang R, Cruz-Bastida J, Gomez-Cardona D, Hayes J, Li K, Chen G Med Phys. 2018; 45(10):4519-4528.
PMID: 30102414 PMC: 7301593. DOI: 10.1002/mp.13119.