Total Synthesis and Stereochemical Assignment of (±)-sorbiterrin A

Overview

Journal J Am Chem Soc

Publisher American Chemical Society

Specialty Chemistry

Date 2014 Feb 20

PMID 24547688

Citations 3

Authors

Chao Qi

Tian Qin

Daisuke Suzuki

John A Porco Jr

Affiliations

Soon will be listed here.

Abstract

A concise, biomimetic approach to sorbiterrin A has been developed employing consecutive Michael additions of a 4-hydroxypyrone to a sorbicillinol derivative and silver nanoparticle-mediated bridged aldol/dehydration to construct the [3.3.1] ring system. The relative stereochemistry of sorbiterrin A was unambiguously confirmed by X-ray crystallographic analysis.

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