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Fiber Typing in Aging Muscle

Overview
Specialty Orthopedics
Date 2014 Feb 11
PMID 24508741
Citations 56
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Abstract

It is accepted widely that fast-twitch muscle fibers are preferentially impacted in aging muscle, yet we hypothesize that this is not valid when aging muscle atrophy becomes severe. In this review, we summarize the evidence of fiber type-specific effect in aging muscle and the potential confounding roles of fibers coexpressing multiple myosin heavy-chain isoforms and their histochemical identification.

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