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Girl Power: Estrogen Promotes HSC Self-renewal

Overview
Journal Cell Stem Cell
Publisher Cell Press
Specialty Cell Biology
Date 2014 Feb 11
PMID 24506879
Citations 4
Authors
Esther Carreras
Susan Kovats
Affiliations
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Abstract

Although some hematopoietic cell types are known to respond to sex hormones, hematopoietic stem cells (HSCs) are generally thought to function similarly in both sexes. Recently in Nature, Nakada et al. (2014) show that HSCs respond to higher levels of estrogen in females, resulting in enhanced self-renewal and increased erythropoiesis.

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