Collapsing Glomerulopathy and Hemolytic Uremic Syndrome Associated with Falciparum Malaria: Completely Reversible Acute Kidney Injury
Overview
Authors
Affiliations
Acute kidney injury (AKI) is one of the most dreaded complications of severe malaria. Herein, we report a case of spontaneous resolution of AKI due to collapsing glomerulopathy (CG) and hemolytic-uremic syndrome (HUS) associated with P. falciparum malaria. Our case report highlights the fact that early intervention on the triggering cause of CG without a long course of steroids may obtain a remission of this severe subset of CG and may obtain a remission of HUS without therapeutic plasmapheresis The etiologic treatment of CG and HUS may avoid progression to end-stage renal disease.
Li J, Docile H, Fisher D, Pronyuk K, Zhao L J Epidemiol Glob Health. 2024; 14(3):561-579.
PMID: 38656731 PMC: 11442732. DOI: 10.1007/s44197-024-00228-2.
Possemiers H, Pollenus E, Prenen F, Knoops S, Koshy P, Van den Steen P Front Cell Infect Microbiol. 2022; 12:915792.
PMID: 36004329 PMC: 9394429. DOI: 10.3389/fcimb.2022.915792.
Butt N, Ahmed E Eur J Med Res. 2022; 27(1):2.
PMID: 34991710 PMC: 8734130. DOI: 10.1186/s40001-021-00627-2.
First Case of COVID-19-Associated Collapsing Glomerulopathy in Sub-Saharan Africa.
Nlandu Y, Makulo J, Pakasa N, Sumaili E, Nkondi C, Bukabau J Case Rep Nephrol. 2020; 2020:8820713.
PMID: 33005463 PMC: 7522604. DOI: 10.1155/2020/8820713.
Azhar M, Alasadi L, Kemnele S, Reiser I, Spitalewitz S Am J Case Rep. 2019; 20:1576-1580.
PMID: 31655844 PMC: 6830302. DOI: 10.12659/AJCR.917722.