Facile Fabrication of Polyanhydride/anesthetic Nanoparticles with Tunable Release Kinetics

Overview

Journal Adv Healthc Mater

Specialties Biomedical Engineering
Biotechnology

Date 2013 Dec 31

PMID 24376136

Citations 4

Authors

Bret D Ulery

Ho-Man Kan

Bryce A Williams

Balaji Narasimhan

Kevin W-H Lo

Lakshmi S Nair

Cato T Laurencin

Affiliations

Soon will be listed here.

Abstract

This work illustrates a two-step strategy for the fabrication of polymer/drug nanoparticles. Utilizing solvent/non-solvent precipitation and gaseous basification, composite nanoparticles with 0-100% drug loadings are fabricated. Drug release kinetics are dictated by nanoparticle composition allowing future tuning for therapeutic applications.

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