The Effect of Community-based Education for Lifestyle Intervention on the Prevalence of Metabolic Syndrome and Its Components: Tehran Lipid and Glucose Study

Overview

Journal Int J Endocrinol Metab

Publisher Brieflands

Specialty Endocrinology

Date 2013 Dec 19

PMID 24348586

Citations 17

Authors

Fereidoun Azizi

Parvin Mirmiran

Amir Abbas Momenan

Farzad Hadaegh

Ali Habibi Moeini

Firoozeh Hosseini

Saleh Zahediasl

Arash Ghanbarian

Farhad Hosseinpanah

Affiliations

Soon will be listed here.

Abstract

Background: It has been shown that life style modification may decrease the prevalence of metabolic syndrome, but this intervention has not been reported in community setting.

Objectives: Effect of lifestyle modification on prevalence of metabolic syndrome and its components were assessed in an urban population.

Materials And Methods: In 6870 participants of Tehran Lipid and Glucose Study aged 20-74 years, the prevalence of metabolic syndrome and its components were measured before and after a 3.6 years interval. Lifestyle intervention was employed at a community level including 2961 individuals and also 3909 subjects which were recruited as controls. Logistic regression analysis was adjusted for age, sex and medications.

Results: After 3.6 years, the rise in the prevalence of metabolic syndrome was less prominent in intervention than control group (P < 0.002 for increase of metabolic syndrome prevalence between groups), with an OR of 0.84 (confidence interval 0.75-0.95). After intervention the prevalence of abdominal obesity, elevated fasting glucose levels, elevated triglyceride and low HDL cholesterol were more prominent in control group, as compared to intervention group.

Conclusions: Community based lifestyle modifications in Tehranian adults delayed rise in the prevalence of metabolic syndrome and some of its components.

Citing Articles

A pragmatic multi-setting healthy lifestyle intervention to improve BMI status in a middle-income population: A potential strategy for individuals at risk.

Yari-Boroujeni R, Cheraghi L, Parvin P, Shiravi F, Masihay-Akbar H, Momenan A Health Promot Perspect. 2025; 14(4):369-379.

PMID: 40041731 PMC: 11873776. DOI: 10.34172/hpp.43196.

The effect of results-based motivating system on metabolic risk factors of non-communicable diseases: A field trial study.

Asadi-Aliabadi M, Karimi S, Mirbaha-Hashemi F, Tehrani-Banihashemi A, Janani L, Babaee E PLoS One. 2024; 19(10):e0311507.

PMID: 39418251 PMC: 11486381. DOI: 10.1371/journal.pone.0311507.

Interplay between Comorbidities and Long COVID: Challenges and Multidisciplinary Approaches.

Ashmawy R, Hammouda E, El-Maradny Y, Aboelsaad I, Hussein M, Uversky V Biomolecules. 2024; 14(7).

PMID: 39062549 PMC: 11275036. DOI: 10.3390/biom14070835.

Bibliometric overview of the Tehran Lipid and Glucose Study (TLGS) publications from 2000 to 2022.

Rezaeizadeh F, Ghazbani A, Nouri M, Bahadoran Z, Mansourzadeh M, Khalili D J Diabetes Metab Disord. 2024; 23(1):343-351.

PMID: 38932887 PMC: 11196460. DOI: 10.1007/s40200-024-01392-9.

Prevalence of Metabolic Syndrome Based on Activity Type and Dietary Habits in Extremely Low-Income Individuals.

Su K, Kim Y, Park Y Nutrients. 2024; 16(11).

PMID: 38892609 PMC: 11175098. DOI: 10.3390/nu16111677.

References

Singh R, Singh N, Rastogi S, Mani U, Niaz M . Effects of diet and lifestyle changes on atherosclerotic risk factors after 24 weeks on the Indian Diet Heart Study. Am J Cardiol. 1993; 71(15):1283-8. DOI: 10.1016/0002-9149(93)90541-j. View

Sullivan V . Prevention and treatment of the metabolic syndrome with lifestyle intervention: where do we start?. J Am Diet Assoc. 2006; 106(5):668-71. DOI: 10.1016/j.jada.2006.03.027. View

Corcoran M, Lamon-Fava S, Fielding R . Skeletal muscle lipid deposition and insulin resistance: effect of dietary fatty acids and exercise. Am J Clin Nutr. 2007; 85(3):662-77. DOI: 10.1093/ajcn/85.3.662. View

Gami A, Witt B, Howard D, Erwin P, Gami L, Somers V . Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies. J Am Coll Cardiol. 2007; 49(4):403-14. DOI: 10.1016/j.jacc.2006.09.032. View

Azizi F, Ghanbarian A, Momenan A, Hadaegh F, Mirmiran P, Hedayati M . Prevention of non-communicable disease in a population in nutrition transition: Tehran Lipid and Glucose Study phase II. Trials. 2009; 10:5. PMC: 2656492. DOI: 10.1186/1745-6215-10-5. View

Momenan A, Delshad M, Mirmiran P, Ghanbarian A, Azizi F . Leisure Time Physical Activity and Its Determinants among Adults in Tehran: Tehran Lipid and Glucose Study. Int J Prev Med. 2011; 2(4):243-51. PMC: 3237267. View

Watkins L, Sherwood A, Feinglos M, Hinderliter A, Babyak M, Gullette E . Effects of exercise and weight loss on cardiac risk factors associated with syndrome X. Arch Intern Med. 2003; 163(16):1889-95. DOI: 10.1001/archinte.163.16.1889. View

Meckling K, Sherfey R . A randomized trial of a hypocaloric high-protein diet, with and without exercise, on weight loss, fitness, and markers of the Metabolic Syndrome in overweight and obese women. Appl Physiol Nutr Metab. 2007; 32(4):743-52. DOI: 10.1139/H07-059. View

Orchard T, Temprosa M, Goldberg R, Haffner S, Ratner R, Marcovina S . The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial. Ann Intern Med. 2005; 142(8):611-9. PMC: 2505046. DOI: 10.7326/0003-4819-142-8-200504190-00009. View

10.

Villareal D, Miller 3rd B, Banks M, Fontana L, Sinacore D, Klein S . Effect of lifestyle intervention on metabolic coronary heart disease risk factors in obese older adults. Am J Clin Nutr. 2006; 84(6):1317-23. DOI: 10.1093/ajcn/84.6.1317. View

11.

Mirmiran P, Hosseini Esfahani F, Mehrabi Y, Hedayati M, Azizi F . Reliability and relative validity of an FFQ for nutrients in the Tehran lipid and glucose study. Public Health Nutr. 2009; 13(5):654-62. DOI: 10.1017/S1368980009991698. View

12.

Muzio F, Mondazzi L, Sommariva D, Branchi A . Long-term effects of low-calorie diet on the metabolic syndrome in obese nondiabetic patients. Diabetes Care. 2005; 28(6):1485-6. DOI: 10.2337/diacare.28.6.1485. View

13.

Noakes M, Keogh J, Foster P, Clifton P . Effect of an energy-restricted, high-protein, low-fat diet relative to a conventional high-carbohydrate, low-fat diet on weight loss, body composition, nutritional status, and markers of cardiovascular health in obese women. Am J Clin Nutr. 2005; 81(6):1298-306. DOI: 10.1093/ajcn/81.6.1298. View

14.

Knowler W, Barrett-Connor E, Fowler S, Hamman R, Lachin J, Walker E . Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002; 346(6):393-403. PMC: 1370926. DOI: 10.1056/NEJMoa012512. View

15.

Azizi F, Salehi P, Etemadi A, Zahedi-Asl S . Prevalence of metabolic syndrome in an urban population: Tehran Lipid and Glucose Study. Diabetes Res Clin Pract. 2003; 61(1):29-37. DOI: 10.1016/s0168-8227(03)00066-4. View

16.

Ainsworth B, Jacobs Jr D, Leon A . Validity and reliability of self-reported physical activity status: the Lipid Research Clinics questionnaire. Med Sci Sports Exerc. 1993; 25(1):92-8. DOI: 10.1249/00005768-199301000-00013. View

17.

Azizi F, Rahmani M, Emami H, Mirmiran P, Hajipour R, Madjid M . Cardiovascular risk factors in an Iranian urban population: Tehran lipid and glucose study (phase 1). Soz Praventivmed. 2003; 47(6):408-26. DOI: 10.1007/s000380200008. View

18.

Gillies C, Abrams K, Lambert P, Cooper N, Sutton A, Hsu R . Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: systematic review and meta-analysis. BMJ. 2007; 334(7588):299. PMC: 1796695. DOI: 10.1136/bmj.39063.689375.55. View

19.

Esposito K, Marfella R, Ciotola M, Di Palo C, Giugliano F, Giugliano G . Effect of a mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trial. JAMA. 2004; 292(12):1440-6. DOI: 10.1001/jama.292.12.1440. View

20.

Lien L, Brown A, Ard J, Loria C, Erlinger T, Feldstein A . Effects of PREMIER lifestyle modifications on participants with and without the metabolic syndrome. Hypertension. 2007; 50(4):609-16. DOI: 10.1161/HYPERTENSIONAHA.107.089458. View