Pathogenesis Related-10 Proteins Are Small, Structurally Similar but with Diverse Role in Stress Signaling

Overview

Journal Mol Biol Rep

Specialty Molecular Biology

Date 2013 Dec 18

PMID 24343423

Citations 40

Authors

Parinita Agarwal

Pradeep K Agarwal

Affiliations

Soon will be listed here.

Abstract

Pathogenesis related-10 proteins are small proteins with cytosolic localization, conserved three dimensional structures and single intron at 185 bp position. These proteins have a broad spectrum of roles significantly in biotic and abiotic stresses. The RNase activity, ligand binding activity, posttranslational modification (phosphorylation) and phytohormone signaling provide some information into the mechanism of the regulation of PR-10 proteins, however the presence of isoforms makes it difficult to decipher its exact mode of function. The involvement of phosphorylation/dephosphorylation events in its activation is interesting and provides unique and unbiased insights into the complexity of its regulation. Studies on upstream region of different PR-10 genes indicate the presence of cis-acting elements for WRKY, RAVI, bZ1P, ERF, SEBF and Pti4 transcription factors indicating their role in regulating PR-10 promoter. In this review, we discuss in detail the structure and mechanism of regulation of PR-10 proteins.

Citing Articles

Protein-Based Mechanism of Wheat Growth Under Salt Stress in Seeds Irradiated with Millimeter Waves.

Komatsu S, Koh R, Yamaguchi H, Hitachi K, Tsuchida K Int J Mol Sci. 2025; 26(1.

PMID: 39796108 PMC: 11720253. DOI: 10.3390/ijms26010253.

Identification and analysis of major latex protein () family genes in responsive to infection by RNA-seq approaches.

Chen H, Li Q, Cheng P, Yan T, Dong C, Hou Z Front Plant Sci. 2024; 15:1511597.

PMID: 39735770 PMC: 11671256. DOI: 10.3389/fpls.2024.1511597.

Heterologous expression of Halostachys caspica pathogenesis-related protein 10 increases salt and drought resistance in transgenic Arabidopsis thaliana.

Cao J, Maitirouzi A, Feng Y, Zhang H, Heng Y, Zhang J Plant Mol Biol. 2024; 115(1):5.

PMID: 39671054 DOI: 10.1007/s11103-024-01536-8.

Comparative transcriptomic and proteomic analyses of two salt-tolerant alfalfa ( L.) genotypes: investigation of the mechanisms underlying tolerance to salt.

Hang J, Song T, Zhang L, Hou W, Liu X, Ma D Front Plant Sci. 2024; 15:1442963.

PMID: 39606676 PMC: 11598528. DOI: 10.3389/fpls.2024.1442963.

Genome-Wide Identification of PR10 Family Members in Durum Wheat: Expression Profile and In Vitro Analyses of TdPR10.1 in Response to Various Stress Conditions.

Khanfir E, Zribi I, Dhouib H, Ghorbel M, Hamdi K, Jrad O Plants (Basel). 2024; 13(22).

PMID: 39599337 PMC: 11597350. DOI: 10.3390/plants13223128.

References

He M, Xu Y, Cao J, Zhu Z, Jiao Y, Wang Y . Subcellular localization and functional analyses of a PR10 protein gene from Vitis pseudoreticulata in response to Plasmopara viticola infection. Protoplasma. 2012; 250(1):129-40. DOI: 10.1007/s00709-012-0384-8. View

Turck F, Zhou A, Somssich I . Stimulus-dependent, promoter-specific binding of transcription factor WRKY1 to Its native promoter and the defense-related gene PcPR1-1 in Parsley. Plant Cell. 2004; 16(10):2573-85. PMC: 520956. DOI: 10.1105/tpc.104.024810. View

Mur L, Brown I, Darby R, Bestwick C, Bi Y, Mansfield J . A loss of resistance to avirulent bacterial pathogens in tobacco is associated with the attenuation of a salicylic acid-potentiated oxidative burst. Plant J. 2000; 23(5):609-21. DOI: 10.1046/j.1365-313x.2000.00825.x. View

Warner S, Scott R, Draper J . Characterisation of a wound-induced transcript from the monocot asparagus that shares similarity with a class of intracellular pathogenesis-related (PR) proteins. Plant Mol Biol. 1992; 19(4):555-61. DOI: 10.1007/BF00026782. View

Mould M, Xu T, Barbara M, Iscove N, Heath M . cDNAs generated from individual epidermal cells reveal that differential gene expression predicting subsequent resistance or susceptibility to rust fungal infection occurs prior to the fungus entering the cell lumen. Mol Plant Microbe Interact. 2003; 16(9):835-45. DOI: 10.1094/MPMI.2003.16.9.835. View

Somssich I, Schmelzer E, Kawalleck P, Hahlbrock K . Gene structure and in situ transcript localization of pathogenesis-related protein 1 in parsley. Mol Gen Genet. 1988; 213(1):93-8. DOI: 10.1007/BF00333403. View

Zubini P, Zambelli B, Musiani F, Ciurli S, Bertolini P, Baraldi E . The RNA hydrolysis and the cytokinin binding activities of PR-10 proteins are differently performed by two isoforms of the Pru p 1 peach major allergen and are possibly functionally related. Plant Physiol. 2009; 150(3):1235-47. PMC: 2705045. DOI: 10.1104/pp.109.139543. View

Bi Y, Kenton P, Mur L, Darby R, Draper J . Hydrogen peroxide does not function downstream of salicylic acid in the induction of PR protein expression. Plant J. 1995; 8(2):235-45. DOI: 10.1046/j.1365-313x.1995.08020235.x. View

Takeuchi K, Gyohda A, Tominaga M, Kawakatsu M, Hatakeyama A, Ishii N . RSOsPR10 expression in response to environmental stresses is regulated antagonistically by jasmonate/ethylene and salicylic acid signaling pathways in rice roots. Plant Cell Physiol. 2011; 52(9):1686-96. DOI: 10.1093/pcp/pcr105. View

10.

Crowell D, John M, Russell D, Amasino R . Characterization of a stress-induced, developmentally regulated gene family from soybean. Plant Mol Biol. 1992; 18(3):459-66. DOI: 10.1007/BF00040662. View

11.

Srivastava S, Fristensky B, Kav N . Constitutive expression of a PR10 protein enhances the germination of Brassica napus under saline conditions. Plant Cell Physiol. 2004; 45(9):1320-4. DOI: 10.1093/pcp/pch137. View

12.

Liu J, Ekramoddoullah A . Characterization, expression and evolution of two novel subfamilies of Pinus monticola cDNAs encoding pathogenesis-related (PR)-10 proteins. Tree Physiol. 2004; 24(12):1377-85. DOI: 10.1093/treephys/24.12.1377. View

13.

Lebel S, Schellenbaum P, Walter B, Maillot P . Characterisation of the Vitis vinifera PR10 multigene family. BMC Plant Biol. 2010; 10:184. PMC: 3095314. DOI: 10.1186/1471-2229-10-184. View

14.

Liu J, Ekramoddoullah A . Root-specific expression of a western white pine PR10 gene is mediated by different promoter regions in transgenic tobacco. Plant Mol Biol. 2003; 52(1):103-20. DOI: 10.1023/a:1023930326839. View

15.

Chen Z, Brown R, Rajasekaran K, Damann K, Cleveland T . Identification of a Maize Kernel Pathogenesis-Related Protein and Evidence for Its Involvement in Resistance to Aspergillus flavus Infection and Aflatoxin Production. Phytopathology. 2008; 96(1):87-95. DOI: 10.1094/PHYTO-96-0087. View

16.

Tashpulatov A, Clement P, Akimcheva S, Belogradova K, Barinova I, Rakhmawaty F . A model system to study the environment-dependent expression of the Bet v 1a gene encoding the major birch pollen allergen. Int Arch Allergy Immunol. 2004; 134(1):1-9. DOI: 10.1159/000077527. View

17.

Lim J, Park C, Huh S, Choi L, Lee G, Kim Y . Capsicum annuum WRKYb transcription factor that binds to the CaPR-10 promoter functions as a positive regulator in innate immunity upon TMV infection. Biochem Biophys Res Commun. 2011; 411(3):613-9. DOI: 10.1016/j.bbrc.2011.07.002. View

18.

Ma W, Qi Z, Smigel A, Walker R, Verma R, Berkowitz G . Ca2+, cAMP, and transduction of non-self perception during plant immune responses. Proc Natl Acad Sci U S A. 2009; 106(49):20995-1000. PMC: 2780315. DOI: 10.1073/pnas.0905831106. View

19.

Wen J, Hoffmann-Sommergruber K, Scheiner O, Breiteneder H . The potential of Betv1 homologues, a nuclear multigene family, as phylogenetic markers in flowering plants. Mol Phylogenet Evol. 1998; 8(3):317-33. DOI: 10.1006/mpev.1997.0447. View

20.

Choi J, Choi D, Lee S, Ryu C, Hwang I . Cytokinins and plant immunity: old foes or new friends?. Trends Plant Sci. 2011; 16(7):388-94. DOI: 10.1016/j.tplants.2011.03.003. View