Synthesis of a Photocontrollable Hydrogen Sulfide Donor Using Ketoprofenate Photocages

Overview

Journal Chem Commun (Camb)

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2013 Nov 28

PMID 24280741

Citations 30

Authors

Naoki Fukushima

Naoya Ieda

Kiyoshi Sasakura

Tetsuo Nagano

Kenjiro Hanaoka

Takayoshi Suzuki

Naoki Miyata

Hidehiko Nakagawa

Affiliations

Soon will be listed here.

Abstract

We report the design, synthesis and application of a directly photocontrollable hydrogen sulfide (H2S) donor, which releases H2S proportionally to the intensity and duration of photoirradiation. Photocontrolled H2S release from this donor was also demonstrated in bovine serum. This H2S donor should be suitable for use in various biological systems.

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