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Primary Structure of Human Salivary Alpha-amylase Gene

Overview
Journal Gene
Specialty Molecular Biology
Date 1986 Jan 1
PMID 2423416
Citations 12
Authors
T Nishide
Y Nakamura
M Emi
T Yamamoto
M Ogawa
T Mori
K Matsubara
Affiliations
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Abstract

A recombinant clone which covers the human salivary alpha-amylase gene in a single insert has been isolated from a human genomic DNA library using a human salivary alpha-amylase cDNA as a probe. Restriction mapping and nucleotide (nt) sequence analysis revealed that this gene is approx. 10 kb long and is separated into eleven exons by ten introns. Its 5'-flanking region has some sequence homology with that of mouse salivary alpha-amylase gene [Schibler et al., J. Mol. Biol. 155 (1982) 247-266].

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