Sirt1-Claudin-1 Crosstalk Regulates Renal Function

Overview

Journal Nat Med

Specialties General Medicine
Molecular Biology

Date 2013 Nov 9

PMID 24202384

Citations 19

Authors

Deepak Nihalani

Katalin Susztak

Affiliations

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Citing Articles

Characterization of diabetic kidney disease in 235 patients: clinical and pathological insights with or without concurrent non-diabetic kidney disease.

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Central role of podocytes in mediating cellular cross talk in glomerular health and disease.

Gujarati N, Chow A, Mallipattu S Am J Physiol Renal Physiol. 2024; 326(3):F313-F325.

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[Research Progress in Stress-Induced Senescence of Renal Tubular Cells in Diabetic Nephropathy].

Yi X, He Y, Chen K Sichuan Da Xue Xue Bao Yi Xue Ban. 2024; 54(6):1085-1090.

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Evaluation of glomerular sirtuin-1 and claudin-1 in the pathophysiology of nondiabetic focal segmental glomerulosclerosis.

Lopes-Goncalves G, Costa-Pessoa J, Pimenta R, Tostes A, Da Silva E, Ledesma F Sci Rep. 2023; 13(1):22685.

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Advances in understanding and treating diabetic kidney disease: focus on tubulointerstitial inflammation mechanisms.

Xu C, Ha X, Yang S, Tian X, Jiang H Front Endocrinol (Lausanne). 2023; 14:1232790.

PMID: 37859992 PMC: 10583558. DOI: 10.3389/fendo.2023.1232790.

References

Chabardes-Garonne D, Mejean A, Aude J, Cheval L, Di Stefano A, Gaillard M . A panoramic view of gene expression in the human kidney. Proc Natl Acad Sci U S A. 2003; 100(23):13710-5. PMC: 263878. DOI: 10.1073/pnas.2234604100. View

George B, Verma R, Soofi A, Garg P, Zhang J, Park T . Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease. J Clin Invest. 2012; 122(2):674-92. PMC: 3266791. DOI: 10.1172/JCI60070. View

Susztak K, Ciccone E, McCue P, Sharma K, Bottinger E . Multiple metabolic hits converge on CD36 as novel mediator of tubular epithelial apoptosis in diabetic nephropathy. PLoS Med. 2005; 2(2):e45. PMC: 549593. DOI: 10.1371/journal.pmed.0020045. View

Wiggins R . The spectrum of podocytopathies: a unifying view of glomerular diseases. Kidney Int. 2007; 71(12):1205-14. DOI: 10.1038/sj.ki.5002222. View

Hasegawa K, Wakino S, Simic P, Sakamaki Y, Minakuchi H, Fujimura K . Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes. Nat Med. 2013; 19(11):1496-504. PMC: 4041199. DOI: 10.1038/nm.3363. View

Susztak K, Raff A, Schiffer M, Bottinger E . Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes. 2005; 55(1):225-33. View

Brosius 3rd F, Alpers C, Bottinger E, Breyer M, Coffman T, Gurley S . Mouse models of diabetic nephropathy. J Am Soc Nephrol. 2009; 20(12):2503-12. PMC: 4075053. DOI: 10.1681/ASN.2009070721. View

Garg P, Holzman L . Podocytes: gaining a foothold. Exp Cell Res. 2012; 318(9):955-63. DOI: 10.1016/j.yexcr.2012.02.030. View

Harris P, Morgan T, Alcorn D, Wilkinson J, RYAN G . The role of the macula densa in renin release: studies by microperfusion. J Hypertens Suppl. 1986; 4(6):S424-7. View

10.

Vaquero A, Reinberg D . Calorie restriction and the exercise of chromatin. Genes Dev. 2009; 23(16):1849-69. PMC: 2725938. DOI: 10.1101/gad.1807009. View

11.

Yoshino J, Mills K, Yoon M, Imai S . Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011; 14(4):528-36. PMC: 3204926. DOI: 10.1016/j.cmet.2011.08.014. View

12.

Hall J, Dominy J, Lee Y, Puigserver P . The sirtuin family's role in aging and age-associated pathologies. J Clin Invest. 2013; 123(3):973-9. PMC: 3582122. DOI: 10.1172/JCI64094. View

13.

Niranjan T, Bielesz B, Gruenwald A, Ponda M, Kopp J, Thomas D . The Notch pathway in podocytes plays a role in the development of glomerular disease. Nat Med. 2008; 14(3):290-8. DOI: 10.1038/nm1731. View