Screening for Lung Cancer with Low-dose Computed Tomography: a Review of Current Status

Overview

Journal J Thorac Dis

Publisher AME Publishing Company

Specialty Pulmonary Medicine

Date 2013 Oct 29

PMID 24163745

Citations 31

Authors

Henry M Marshall

Rayleen V Bowman

Ian A Yang

Kwun M Fong

Christine D Berg

Affiliations

Soon will be listed here.

Abstract

Screening using low-dose computed tomography (CT) represents an exciting new development in the struggle to improve outcomes for people with lung cancer. Randomised controlled evidence demonstrating a 20% relative lung cancer mortality benefit has led to endorsement of screening by several expert bodies in the US and funding by healthcare providers. Despite this pivotal result, many questions remain regarding technical and logistical aspects of screening, cost-effectiveness and generalizability to other settings. This review discusses the rationale behind screening, the results of on-going trials, potential harms of screening and current knowledge gaps.

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