Microfluidic Chip-based Technologies: Emerging Platforms for Cancer Diagnosis

Overview

Journal BMC Biotechnol

Publisher Biomed Central

Specialty Biotechnology

Date 2013 Sep 28

PMID 24070124

Citations 15

Authors

Li Ying

Qi Wang

Affiliations

Soon will be listed here.

Abstract

The development of early and personalized diagnostic protocols is considered the most promising avenue to decrease mortality from cancer and improve outcome. The emerging microfluidic-based analyzing platforms hold high promises to fulfill high-throughput and high-precision screening with reduced equipment cost and low analysis time, as compared to traditional bulky counterparts in bench-top laboratories. This article overviewed the potential applications of microfluidic technologies for detection and monitoring of cancer through nucleic acid and protein biomarker analysis. The implications of the technologies in cancer cytology that can provide functional personalized diagnosis were highlighted. Finally, the future niches for using microfluidic-based systems in tumor screening were briefly discussed.

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