» Articles » PMID: 24046679

2-Oxo-2H-chromen-4-yl Propionate

Overview
Date 2013 Sep 19
PMID 24046679
Citations 3
Authors
Affiliations
Soon will be listed here.
Abstract

In the title compound, C12H10O4, the atoms of the 2-oxo-2H-chromene ring system and the non-H atoms of the 4-substituent all lie on a crystallographic mirror plane. The mol-ecular structure exhibits an intra-molecular C-H⋯O hydrogen bond, which generates an S(6) ring. In the crystal, mol-ecules form R 3 (2)(12) trimeric units via C-H⋯O inter-actions which propagate into layers parallel to the ac plane. These layers are linked by weak C-H⋯O inter-actions along the [010] direction, generating a three-dimensional network.

Citing Articles

Crystal structure, Hirshfeld surface, DFT, mol-ecular docking of 1-[(6--butyl-2-oxo-2-chromen-4-yl)meth-yl]-4,4-di-methyl-piperidine-2,6-dione and cytotoxic effects on breast cancer (MDA-MB 231), human alveolar basal epithelial (A549) cell lines.

Sunitha Kumari M, Harish Kumar M, Deevith D, Devarajegowda H, Palakshamurthy B Acta Crystallogr E Crystallogr Commun. 2025; 81(Pt 3):257-263.

PMID: 40071047 PMC: 11891594. DOI: 10.1107/S2056989025001550.


Synthesis and structure of 2-oxo-2-chromen-4-yl 4-bromo-benzoate: work carried out as part of the CNRS AFRAMED project.

Bationo V, Kambo K, Sorgho B, Sombie C, Thiam E, Semde R Acta Crystallogr E Crystallogr Commun. 2025; 81(Pt 3):200-203.

PMID: 40071046 PMC: 11891593. DOI: 10.1107/S2056989025000246.


The crystal structures of two new coumarin derivatives: 2-(4-{2-[(2-oxo-2-chromen-4-yl)-oxy]acet-yl}piperazin-1-yl)acetamide and -(2,4-di-meth-oxy-benz-yl)-2-[(2-oxo-2-chromen-4-yl)-oxy]acetamide.

Syed Abuthahir S, NizamMohideen M, Viswanathan V, Govindhan M, Subramanian K Acta Crystallogr E Crystallogr Commun. 2019; 75(Pt 4):482-488.

PMID: 31161061 PMC: 6509693. DOI: 10.1107/S2056989019003736.


Crystal structure of 2-oxo-2-chromen-7-yl 4-fluoro-benzoate.

Abou A, Yoda J, Djande A, Coussan S, Zoueu T Acta Crystallogr E Crystallogr Commun. 2018; 74(Pt 5):761-765.

PMID: 29850108 PMC: 5947504. DOI: 10.1107/S205698901800614X.


2-Oxo-2-chromen-7-yl 4--butyl-benzoate.

Ouedraogo M, Abou A, Djande A, Ouari O, Zoueu T Acta Crystallogr E Crystallogr Commun. 2018; 74(Pt 4):530-534.

PMID: 29765760 PMC: 5946982. DOI: 10.1107/S2056989018004188.

References
1.
Vukovic N, Sukdolak S, Solujic S, Niciforovic N . An efficient synthesis and antioxidant properties of novel imino and amino derivatives of 4-hydroxy coumarins. Arch Pharm Res. 2010; 33(1):5-15. DOI: 10.1007/s12272-010-2220-z. View

2.
Abou A, Djande A, Danger G, Saba A, Kakou-Yao R . 2-Oxo-2H-chromen-4-yl 4-meth-oxy-benzoate. Acta Crystallogr Sect E Struct Rep Online. 2013; 68(Pt 12):o3438-9. PMC: 3589019. DOI: 10.1107/S1600536812047666. View

3.
Spek A . Structure validation in chemical crystallography. Acta Crystallogr D Biol Crystallogr. 2009; 65(Pt 2):148-55. PMC: 2631630. DOI: 10.1107/S090744490804362X. View

4.
Yu D, Morris-Natschke S, Lee K . New developments in natural products-based anti-AIDS research. Med Res Rev. 2006; 27(1):108-32. DOI: 10.1002/med.20075. View

5.
Yu D, Suzuki M, Xie L, Morris-Natschke S, Lee K . Recent progress in the development of coumarin derivatives as potent anti-HIV agents. Med Res Rev. 2003; 23(3):322-45. DOI: 10.1002/med.10034. View