Anatomical Characteristics of the Cerebral Surface in Bulimia Nervosa

Overview

Journal Biol Psychiatry

Publisher Elsevier

Specialty Psychiatry

Date 2013 Aug 28

PMID 23978404

Citations 33

Authors

Rachel Marsh

Mihaela Stefan

Ravi Bansal

Xuejun Hao

B Timothy Walsh

Bradley S Peterson

Affiliations

Soon will be listed here.

Abstract

Background: The aim of this study was to examine morphometric features of the cerebral surface in adolescent and adult female subjects with bulimia nervosa (BN).

Methods: Anatomical magnetic resonance images were acquired from 34 adolescent and adult female subjects with BN and 34 healthy age-matched control subjects. We compared the groups in the morphological characteristics of their cerebral surfaces while controlling for age and illness duration.

Results: Significant reductions of local volumes on the brain surface were detected in frontal and temporoparietal areas in the BN compared with control participants. Reductions in inferior frontal regions correlated inversely with symptom severity, age, and Stroop interference scores in the BN group.

Conclusions: These findings suggest that local volumes of inferior frontal regions are smaller in individuals with BN compared with healthy individuals. These reductions along the cerebral surface might contribute to functional deficits in self-regulation and to the persistence of these deficits over development in BN.

Citing Articles

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Chmiel J, Stepien-Slodkowska M J Clin Med. 2024; 13(18).

PMID: 39336850 PMC: 11432543. DOI: 10.3390/jcm13185364.

Cortical thickness and childhood eating behaviors: differences according to sex and age, and relevance for eating disorders.

Breton E, Khundrakpam B, Jeon S, Evans A, Booij L Eat Weight Disord. 2024; 29(1):47.

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Editorial: Neurological, psychological and endocrine markers of eating disorders and obesity.

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Exploration of the relationships between clinical traits and functional connectivity based on surface morphology abnormalities in bulimia nervosa.

Li W, Wang M, Wu G, Wang J, Li X, Yang Z Brain Behav. 2023; 13(4):e2930.

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