Quality of Sleep in Patients with Parkinson's Disease

Overview

Journal Int J Prev Med

Date 2013 Jun 19

PMID 23776729

Citations 7

Authors

Mohammad Reza Najafi

Ahmad Chitsaz

Zahra Askarian

Mohammad Amin Najafi

Affiliations

Soon will be listed here.

Abstract

Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder causing motor and non-motor symptoms. The latter are common and include autonomic dysfunction, cognitive impairment, and sleep difficulties. Many of the non-motor aspects of PD such as sleep disturbance are more common and significantly affect the day-to-day activities of patients and their quality of life. The most important aim of this study was to evaluate the sleep quality in patients with PD.

Methods: This case-control study was performed on patients with PD referred to the Neurology Clinic of our teaching hospital in 2011. Thirty-four patients with PD and 34 healthy people as control group were enrolled in this study. Sleep quality of patients and control was evaluated by Parkinson's disease sleep scale (PDSS) questionnaire. PDSS is a reliable and valid tool to measure sleep disorders in PD.

Results: The mean total PDSS score in patient group was 55.29 (SD = 26.92) indicating moderate to severe sleep disturbances whereas, the mean total score in control group was 20.34 (SD = 10.65). Difference between the two groups' mean scores was significant (P < 0.05).

Conclusions: Our study demonstrated that patients with PD experienced poorer nocturnal sleep quality than the control group.

Citing Articles

Clinical characteristics in early Parkinson's disease with excessive daytime sleepiness: A cross-sectional and longitudinal study.

Liu Y, Xue L, Zhao J, Dou K, Wang G, Xie A Clin Transl Sci. 2023; 16(10):2033-2045.

PMID: 37551840 PMC: 10582661. DOI: 10.1111/cts.13610.

Sleep Quality and Levodopa Intestinal Gel Infusion in Parkinson's Disease: A Pilot Study.

de Fabregues O, Ferre A, Romero O, Quintana M, Alvarez-Sabin J Parkinsons Dis. 2018; 2018:8691495.

PMID: 30515291 PMC: 6236977. DOI: 10.1155/2018/8691495.

Cortical Phase-Amplitude Coupling in a Progressive Model of Parkinsonism in Nonhuman Primates.

Devergnas A, Caiola M, Pittard D, Wichmann T Cereb Cortex. 2017; 29(1):167-177.

PMID: 29190329 PMC: 6294400. DOI: 10.1093/cercor/bhx314.

Sleep Dysfunction in Parkinson's Disease.

Selvaraj V, Keshavamurthy B J Clin Diagn Res. 2016; 10(2):OC09-12.

PMID: 27042494 PMC: 4800560. DOI: 10.7860/JCDR/2016/16446.7208.

Meta-analyses of seven polymorphisms with Parkinson's disease.

Dai D, Wang Y, Zhou X, Tao J, Jiang D, Zhou H Biomed Rep. 2014; 2(6):886-892.

PMID: 25279164 PMC: 4179736. DOI: 10.3892/br.2014.324.

References

Covassin N, Neikrug A, Liu L, Corey-Bloom J, Loredo J, Palmer B . Clinical correlates of periodic limb movements in sleep in Parkinson's disease. J Neurol Sci. 2012; 316(1-2):131-6. PMC: 3321115. DOI: 10.1016/j.jns.2012.01.004. View

Norlinah M, Afidah K, Noradina A, Shamsul A, Hamidon B, Sahathevan R . Sleep disturbances in Malaysian patients with Parkinson's disease using polysomnography and PDSS. Parkinsonism Relat Disord. 2009; 15(9):670-4. DOI: 10.1016/j.parkreldis.2009.02.012. View

Mayer G, Jennum P, Riemann D, Dauvilliers Y . Insomnia in central neurologic diseases--occurrence and management. Sleep Med Rev. 2011; 15(6):369-78. DOI: 10.1016/j.smrv.2011.01.005. View

Nomura T, Inoue Y, Kagimura T, Uemura Y, Nakashima K . Utility of the REM sleep behavior disorder screening questionnaire (RBDSQ) in Parkinson's disease patients. Sleep Med. 2011; 12(7):711-3. DOI: 10.1016/j.sleep.2011.01.015. View

Martinez-Martin P, Rodriguez-Blazquez C, Abe K, Bhattacharyya K, Bloem B, Carod-Artal F . International study on the psychometric attributes of the non-motor symptoms scale in Parkinson disease. Neurology. 2009; 73(19):1584-91. DOI: 10.1212/WNL.0b013e3181c0d416. View

Menza M, Dobkin R, Marin H, Bienfait K . Sleep disturbances in Parkinson's disease. Mov Disord. 2010; 25 Suppl 1:S117-22. PMC: 2840057. DOI: 10.1002/mds.22788. View

Chaudhuri K, Pal S, DiMarco A, Whately-Smith C, Bridgman K, Mathew R . The Parkinson's disease sleep scale: a new instrument for assessing sleep and nocturnal disability in Parkinson's disease. J Neurol Neurosurg Psychiatry. 2002; 73(6):629-35. PMC: 1757333. DOI: 10.1136/jnnp.73.6.629. View

Nogawa S, Takahashi H, Hattori N . [The development and validation of a new comprehensive self-completing questionnaire for symptoms in Parkinson's disease (MASAC-PD 31)]. Rinsho Shinkeigaku. 2011; 51(5):321-9. DOI: 10.5692/clinicalneurol.51.321. View

Naismith S, Hickie I, Lewis S . The role of mild depression in sleep disturbance and quality of life in Parkinson's disease. J Neuropsychiatry Clin Neurosci. 2010; 22(4):384-9. DOI: 10.1176/jnp.2010.22.4.384. View

10.

McSharry C . Parkinson disease: Skin patch improves sleep in PD. Nat Rev Neurol. 2011; 7(2):64. DOI: 10.1038/nrneurol.2010.208. View

11.

Stavitsky K, Cronin-Golomb A . Sleep quality in Parkinson disease: an examination of clinical variables. Cogn Behav Neurol. 2011; 24(2):43-9. PMC: 3126883. DOI: 10.1097/WNN.0b013e31821a4a95. View

12.

Scheller D, Durmuller N, Moser P, Porsolt R . Continuous stimulation of dopaminergic receptors by rotigotine does not interfere with the sleep-wake cycle in the rat. Eur J Pharmacol. 2008; 584(1):111-7. DOI: 10.1016/j.ejphar.2008.01.038. View

13.

Martinez-Martin P, Visser M, Rodriguez-Blazquez C, Marinus J, Chaudhuri K, van Hilten J . SCOPA-sleep and PDSS: two scales for assessment of sleep disorder in Parkinson's disease. Mov Disord. 2008; 23(12):1681-8. DOI: 10.1002/mds.22110. View

14.

Jauregui-Barrutia A, Tijero-Merino B, Gomez-Esteban J, Zarranz J . [Sleep disorders in Parkinson's disease: REM sleep behaviour disorder and restless legs syndrome]. Rev Neurol. 2010; 50 Suppl 2:S15-9. View

15.

Margis R, Donis K, Schonwald S, Fagondes S, Monte T, Martin-Martinez P . Psychometric properties of the Parkinson's Disease Sleep Scale--Brazilian version. Parkinsonism Relat Disord. 2009; 15(7):495-9. DOI: 10.1016/j.parkreldis.2008.12.008. View

16.

Vibha D, Shukla G, Singh S, Goyal V, Srivastava A, Behari M . Lower prevalence of sleep disturbances in familial versus sporadic Parkinson's disease: a questionnaire based study. J Neurol Sci. 2010; 295(1-2):27-30. DOI: 10.1016/j.jns.2010.05.024. View

17.

Iranzo de Riquer A, Bergareche A, Campos V . Sleep disorders in Parkinson disease. Neurologist. 2011; 17(6 Suppl 1):S38-42. DOI: 10.1097/NRL.0b013e31823966f8. View

18.

Trenkwalder C, Kohnen R, Hogl B, Metta V, Sixel-Doring F, Frauscher B . Parkinson's disease sleep scale--validation of the revised version PDSS-2. Mov Disord. 2011; 26(4):644-52. DOI: 10.1002/mds.23476. View

19.

Muller T, Jugel C, Ehret R, Ebersbach G, Bengel G, Muhlack S . Elevation of total homocysteine levels in patients with Parkinson's disease treated with duodenal levodopa/carbidopa gel. J Neural Transm (Vienna). 2011; 118(9):1329-33. DOI: 10.1007/s00702-011-0614-9. View

20.

Raggi A, Leonardi M, Carella F, Soliveri P, Albanese A, Romito L . Impact of nonmotor symptoms on disability in patients with Parkinson's disease. Int J Rehabil Res. 2011; 34(4):316-20. DOI: 10.1097/MRR.0b013e32834d4b66. View