Propranolol in Use for Treatment of Complex Infant Hemangiomas: Literature Review Regarding Current Guidelines for Preassessment and Standards of Care Before Initiation of Therapy

Overview

Journal ScientificWorldJournal

Publisher Wiley

Specialty Biology

Date 2013 Jun 15

PMID 23766715

Citations 8

Authors

Andreas Fette

Affiliations

Soon will be listed here.

Abstract

In 2008, the positive effects of propranolol on infantile hemangiomas (IH) have been discovered serendipitously by Léauté-Labrèze and her coworkers. Since then, propranolol has been in use in allday clinical practice worldwide for treatment of IH. It even caused some kind of paradigm shift in the overall management of these lesions, though propranolol is still not FDA approved, respectively, in "off-label" use for this indication in the majority of institutions. Thus, the aim of this communication is to evaluate the literature for current evidence regarding guidelines for preassessment and standards of care before initiation of therapy.

Citing Articles

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Propranolol-induced hyperkalemia in infantile hemangioma patients: How serious is it?.

Alakeel A, Alsalman H, Alotaibi G, Somily H, Alsohime F J Family Med Prim Care. 2023; 11(11):6944-6948.

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Management of Head and Neck Hemangiomas in Adults: Oral Propranolol Versus Oral Itraconazole in Conjugation with Injection Sodium Tetra Decyl Sulphate.

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Deep coma in a child treated with propranolol for infantile hemangioma.

Bakalli I, Kola E, Lluka R, Celaj E, Sala D, Gjeta I BMC Pediatr. 2019; 19(1):216.

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Propranolol pharmacokinetics in infants treated for Infantile Hemangiomas requiring systemic therapy: Modeling and dosing regimen recommendations.

Del Frari L, Leaute-Labreze C, Guibaud L, Barbarot S, Lacour J, Chaumont C Pharmacol Res Perspect. 2018; 6(3):e00399.

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