» Articles » PMID: 21402965

Use of Propranolol in Treating Hemangiomas

Overview
Date 2011 Mar 16
PMID 21402965
Citations 8
Authors
Affiliations
Soon will be listed here.
Abstract

Question: I see many children with infantile hemangiomas and have read about new therapeutic options such as propranolol. Is this medication effective and safe for treating hemangiomas in children?

Answer: Most infantile hemangiomas resolve spontaneously without any need for therapy. In many case series, propranolol has been shown to be effective and safe in treating hemangiomas that cause complications. Further studies are required to determine the optimal dose and duration of propranolol treatment for problematic hemangiomas.

Citing Articles

Hematohidrosis in Pediatric Practice - a Case Report and Review of the Literature.

Matsyura O, Besh L, Jefimova S, Khrystyna S, Gerasymov S Acta Med Litu. 2024; 31(1):12-21.

PMID: 38978871 PMC: 11227682. DOI: 10.15388/Amed.2024.31.1.2.


Enucleation versus hepatectomy for hepatic hemangiomas: A meta-analysis.

Jiang B, Shen Z, Fang X, Wang X Front Surg. 2022; 9:960768.

PMID: 35965862 PMC: 9366102. DOI: 10.3389/fsurg.2022.960768.


Oral Atenolol versus Propranolol in the Treatment of Infantile Hemangioma: A Systematic Review and Meta-Analysis.

Pattanshetti S, Mahalmani V, Sarma P, Kaur H, Ali M, Malik M J Indian Assoc Pediatr Surg. 2022; 27(3):279-286.

PMID: 35733601 PMC: 9208683. DOI: 10.4103/jiaps.jiaps_3_21.


Submerged Eutectic-Assisted, Solvent-Free Mechanochemical Formation of a Propranolol Salt and Its Other Multicomponent Solids.

Bialek K, Wojnarowska Z, Skotnicki M, Twamley B, Paluch M, Tajber L Pharmaceutics. 2021; 13(12).

PMID: 34959406 PMC: 8703429. DOI: 10.3390/pharmaceutics13122125.


Enucleation versus hepatectomy for giant hepatic haemangiomas: a meta-analysis.

Cheng W, Qi Y, Wang B, Tian L, Huang W, Chen Y Ann R Coll Surg Engl. 2016; 99(3):237-241.

PMID: 27869486 PMC: 5450283. DOI: 10.1308/rcsann.2016.0349.


References
1.
Chamlin S, Haggstrom A, Drolet B, Baselga E, Frieden I, Garzon M . Multicenter prospective study of ulcerated hemangiomas. J Pediatr. 2007; 151(6):684-9, 689.e1. DOI: 10.1016/j.jpeds.2007.04.055. View

2.
Bennett M, Fleischer Jr A, Chamlin S, Frieden I . Oral corticosteroid use is effective for cutaneous hemangiomas: an evidence-based evaluation. Arch Dermatol. 2001; 137(9):1208-13. DOI: 10.1001/archderm.137.9.1208. View

3.
Lawley L, Siegfried E, Todd J . Propranolol treatment for hemangioma of infancy: risks and recommendations. Pediatr Dermatol. 2009; 26(5):610-4. DOI: 10.1111/j.1525-1470.2009.00975.x. View

4.
Chang L, Haggstrom A, Drolet B, Baselga E, Chamlin S, Garzon M . Growth characteristics of infantile hemangiomas: implications for management. Pediatrics. 2008; 122(2):360-7. DOI: 10.1542/peds.2007-2767. View

5.
Leaute-Labreze C, Dumas de la Roque E, Hubiche T, Boralevi F, Thambo J, Taieb A . Propranolol for severe hemangiomas of infancy. N Engl J Med. 2008; 358(24):2649-51. DOI: 10.1056/NEJMc0708819. View