R-loops in Bacterial Transcription: Their Causes and Consequences

Overview

Journal Transcription

Specialty Molecular Biology

Date 2013 Jun 13

PMID 23756343

Citations 31

Authors

J Gowrishankar

J Krishna Leela

K Anupama

Affiliations

Soon will be listed here.

Abstract

Nascent untranslated transcripts in bacteria are prone to generating RNA-DNA hybrids (R-loops); Rho-dependent transcription termination acts to reduce their prevalence. Here we discuss the mechanisms of R-loop formation and growth inhibition in bacteria.

Citing Articles

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Translocating RNA polymerase generates R-loops at DNA double-strand breaks without any additional factors.

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